Species-specific gB ectodomain interactions and cytoplasmic domain stability regulate herpes simplex virus fusion. [PDF]
Fan Q, Longnecker R, Connolly SA.
europepmc +1 more source
Immune checkpoint-based biomarkers for therapeutic response in patients with multiple sclerosis. [PDF]
López-Molina M +12 more
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Immune landscape of gingivo-buccal oral cancer indicates high enrichment of immune-related gene sets in tumors of a large proportion of patients. [PDF]
Das D +6 more
europepmc +1 more source
Genetically determined causality between immune cells and anxiety disorders: A Mendelian randomization study. [PDF]
Liu J +6 more
europepmc +1 more source
Immune Cell Causality and Glucocorticoid Trade-Off in Frozen Shoulder: Integrative MR-RNA-Seq Analysis. [PDF]
Song B +6 more
europepmc +1 more source
Immune checkpoints in immune response to glioma: two sides of the same coin. [PDF]
Musatova O +3 more
europepmc +1 more source
Blockade of HVEM for Prostate Cancer Immunotherapy in Humanized Mice
International audienceThe herpes virus entry mediator (HVEM) delivers a negative signal to T cells mainly through the B and T lymphocyte attenuator (BTLA) molecule.
Daniel Olive +2 more
exaly +2 more sources
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HVEM-derived peptides as inhibitors of HVEM/LIGHT complex formation
Bioorganic ChemistryT cells are important targets for therapeutic intervention in many diseases. Modifying T cell activation via immune checkpoints plays a central role in such approaches. The HVEM/LIGHT complex is one of the stimulatory immune checkpoints involved in T cell activation, and binding of these proteins results in proliferation and development of effector ...
Piotr Ciura +6 more
openaire +3 more sources
Hvem får, og hvem får ikke en Nobelpris?
Samfundsøkonomen, 2017Det er fristende at søge et mønster i tildelingerne af Nobelprisen i økonomi over de knap 50 år, hvor den har været uddelt, men udover ret oplagte mønstre som et timelag på 30 år fra den forskning, der indgår i begrundelsen, til den faktiske tildeling, er det svært at aflæse nogen systematik.
Nanna Fink, Hans Keiding
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HVEM network signaling in cancer
2019Somatic mutations in cancer cells may influence tumor growth, survival, or immune interactions in their microenvironment. The tumor necrosis factor receptor family member HVEM (TNFRSF14) is frequently mutated in cancers and has been attributed a tumor suppressive role in some cancer contexts.
John R, Šedý, Parham, Ramezani-Rad
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