In Vivo Formation of Stable Hyaline Cartilage by Naïve Human Bone Marrow Stromal Cells with Modified Fibrin Microbeads [PDF]
Stem Cells Translational Medicine, 2019 Osteoarthritic and other types of articular cartilage defects never heal on their own. Medicinal and surgical approaches are often ineffective, and the supply of autologous chondrocytes for tissue engineering is very limited.
Sergei A. Kuznetsov +5 more
doaj +4 more sources
Hyaline Cartilage Microtissues Engineered from Adult Dedifferentiated Chondrocytes: Safety and Role of WNT Signaling. [PDF]
Stem Cells Transl Med, 2022 The repair of damaged articular cartilage is an unmet medical need. Chondrocyte-based cell therapy has been used to repair cartilage for over 20 years despite current limitations.
Kutaish H +18 more
europepmc +4 more sources
Stem Cells and Extrusion 3D Printing for Hyaline Cartilage Engineering [PDF]
Cells, 2020 Hyaline cartilage is deficient in self-healing properties. The early treatment of focal cartilage lesions is a public health challenge to prevent long-term degradation and the occurrence of osteoarthritis.
Océane Messaoudi +5 more
doaj +3 more sources
Is thickened hyaline cartilage on ultrasound a sign of osteoarthritis? A within-person, between-joint pilot study [PDF]
BMC RheumatologyObjective To determine whether the presence of conventional radiography (CR)-detected osteophytes is associated with focal thickening of the hyaline cartilage by ultrasound (US) in the same area of the metacarpal head in a within-person, between-joint ...
Edoardo Cipolletta +4 more
doaj +4 more sources
Treatment of Knee Osteochondral Lesions Using a Novel Clot of Autologous Plasma Rich in Growth Factors Mixed with Healthy Hyaline Cartilage Chips and Intra-Articular Injection of PRGF [PDF]
Case Reports in Orthopedics, 2017 Knee cartilage or osteochondral lesions are common and challenging injuries. To date, most symptomatic lesions warrant surgical treatment. We present two cases of patients with knee osteochondral defects treated with a one-step surgical procedure ...
Ramón Cugat +9 more
doaj +3 more sources
Functional MRI for evaluation of hyaline cartilage extracelullar matrix, a physiopathological-based approach. [PDF]
Br J Radiol, 2019 MRI of articular cartilage (AC) integrity has potential to become a biomarker for osteoarthritis progression. Traditional MRI sequences evaluate AC morphology, allowing for the measurement of thickness and its change over time.
Martín Noguerol T +5 more
europepmc +4 more sources
Strategies to Convert Cells into Hyaline Cartilage: Magic Spells for Adult Stem Cells. [PDF]
Int J Mol Sci, 2022 Damaged hyaline cartilage gradually decreases joint function and growing pain significantly reduces the quality of a patient’s life. The clinically approved procedure of autologous chondrocyte implantation (ACI) for treating knee cartilage lesions has ...
Kurenkova AD +4 more
europepmc +2 more sources
Biophysical Stimuli: A Review of Electrical and Mechanical Stimulation in Hyaline Cartilage. [PDF]
Cartilage, 2019 Vaca-González JJ +5 more
europepmc +4 more sources
Cells, 2021 Articular cartilage defects represent an inciting factor for future osteoarthritis (OA) and degenerative joint disease progression. Despite multiple clinically available therapies that succeed in providing short term pain reduction and restoration of ...
Hallie Thorp +5 more
doaj +2 more sources
Pondering the Potential of Hyaline Cartilage-Derived Chondroprogenitors for Tissue Regeneration: A Systematic Review. [PDF]
Cartilage, 2021 Objective Chondroprogenitors have recently gained prominence due to promising results seen in in vitro and animal studies as a potential contender in cell-based therapy for cartilage repair. Lack of consensus regarding nomenclature, isolation techniques,
Vinod E +3 more
europepmc +2 more sources