Results 171 to 180 of about 2,588 (196)

Carnosine and Retinol Synergistically Inhibit UVB-Induced PGE₂ Synthesis in Human Keratinocytes through the Up-Regulation of Hyaluronan Synthase 2. [PDF]

Biomol Ther (Seoul)
Park IG, Jin SH, An S, Ki MW, Park WS, Kim HJ, Na Y, Noh M.   +7 more
europepmc   +1 more source

Platelet Hyaluronan Synthase 3 Regulates Thrombin Signaling and Adhesion to Fibrinogen Under Venous Shear

Kimberly A. Queisser, Lonnie Smith, GM Leung, Nansy Albtoush, Rebecca A. Mellema, Aaron C. Petrey   +5 more
openalex   +1 more source

Generation of shark Single-Domain antibodies as an aid for Cryo-EM structure determination of membrane Proteins: Use hyaluronan synthase as an example

Penghui Deng, Xiaoyue Zhang, Jianqing Wen, Mingce Xu, Pengwei Li, Hao Wang, Yunchen Bi   +6 more
openalex   +1 more source

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Role of hyaluronan and hyaluronan synthase in endometrial cancer

Oncology Reports, 2005
The aim of this study was to determine if the immunohistochemical expression of hyaluronan synthase (HAS) and serum levels of hyaluronan correlate with the clinicopathological manifestations of endometrial carcinoma. Sera were obtained from 59 endometrial cancer patients and 22 post-menopausal healthy women.
Tameko Kishida, Kanako Fusano, Lisheng Zhuo, Hiromitsu Yabushita, Masayoshi Noguchi, Koji Kimata, Naoki Itano, Kouhei Kanyama   +7 more
openaire   +3 more sources

Hyaluronan synthases and hyaluronidases in nasal polyps [PDF]

European Archives of Oto-Rhino-Laryngology, 2015
Nasal polyps (NPs) are benign lesions of nasal and paranasal sinuses mucosa affecting 1-4 % of all adults. Nasal polyposis affects the quality of patient's life as it causes nasal obstruction, postnasal drainage, purulent nasal discharge, hyposmia or anosmia, chronic sinusitis, facial pain and snoring.
Demitrios H. Vynios, S. Filou, T. Panogeorgou, E. Tserbini, Panos Goumas, N. S. Mastronikolis, Stephanos Naxakis, T A Papadas   +7 more
openaire   +2 more sources

The Hyaluronan Synthase Catalyzes the Synthesis and Membrane Translocation of Hyaluronan

Journal of Molecular Biology, 2012
Hyaluronan (HA), an extracellular linear polysaccharide of alternating N-acetyl-glucosamine and glucuronic acid residues, is ubiquitously expressed in vertebrates, where it affects a broad spectrum of physiological processes, including cell adhesion, migration and differentiation. The HA polymer is synthesized on the cytosolic side of the cell membrane
Joshua T. McNamara, Caitlin Hubbard, Caleigh M. Azumaya, Jochen Zimmer, Mehul S. Patel   +4 more
openaire   +3 more sources

Hyaluronan and Hyaluronan Synthases: Potential Therapeutic Targets in Cancer

Current Drug Target -Cardiovascular & Hematological Disorders, 2005
Current models of oncogenesis describe cancer as a progression of genetic mutations in a tumor cell mass. However, tumors are more than a clonal expansion of malignant cells. Tumors are heterogeneous, with a complex 3D structure, analogous to organs comprised of different tissues.
Linda M. Pilarski, Sophia Adamia, Christopher A. Maxwell   +2 more
openaire   +3 more sources

Analysis of Hyaluronan Synthase Activity

2014
Hyaluronan (HA) is a component of the extracellular matrix that is involved in many physiological and pathological processes. As HA modulates several functions (i.e., cell proliferation and migration, inflammation), its presence in the tissues can have positive or negative effects.
Davide Vigetti, Evgenia Karousou, Manuela Viola, Alberto Passi   +3 more
openaire   +3 more sources

Hyaluronan and hyaluronan synthases expression and localization in embryonic mouse molars

Journal of Molecular Histology, 2016
Hyaluronan (HA) and hyaluronan synthases (HASs) have been shown to play critical roles in embryogenesis and organ development. However, there have not been any studies examining HA and HAS expression and localization during tooth development. The present study was designed to investigate the expression of HA and three isoforms of HASs (HAS1, 2, 3) in ...
Guofeng Yang, Shouliang Zhao, Shouliang Zhao, Wenping Cai, Beizhan Jiang, Shangfeng Liu   +5 more
openaire   +3 more sources