Results 31 to 40 of about 265,910 (261)
Functional Characteristics and Catalytic Mechanisms of the Bacterial Hyaluronan Synthases [PDF]
IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2002 Paul H. Weigel
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Cervical expression of hyaluronan synthases varies with the stage of the estrous cycle in the ewe [PDF]
Theriogenology, 2012 Karen L Perry +4 more
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Targeting Hyaluronan Synthesis in Cancer: A Road Less Travelled
Biologics, 2023 Hyaluronan is one of the major components of the extracellular matrix and is involved in the regulation of multiple processes in both human physiology and disease.
Theodoros Karalis
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Glycobiology, 2023 Hyaluronan (HA), the essential [-3-GlcNAc-1-β-4-GlcA-1-β-]n matrix polysaccharide in vertebrates and molecular camouflage coating in select pathogens, is polymerized by “HA synthase” (HAS) enzymes.
P. DeAngelis, Jochen Zimmer
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Hyaluronan Synthase 1: A Novel Candidate Gene Associated With Late-Onset Non-syndromic Hereditary Hearing Loss [PDF]
Clinical and Experimental Otorhinolaryngology, 2022 Objectives Hyaluronan synthase 1 (HAS1) is a membrane-bound protein that is abundant in the epidermis and dermis, and it is important for skin function. However, its association with hearing loss has not yet been studied.
Alphonse Umugire +5 more
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PP2B and ERK1/2 regulate hyaluronan synthesis of HT168 and WM35 human melanoma cell lines [PDF]
, 2020 Hyaluronan (HA) is the major glycosaminoglycan component of the extracellular matrix in either normal or malignant tissues and it may affect proliferation, motility and differentiation of various cell types.
Gergely, Pál +8 more
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Hyaluronan: Metabolism and Function
Biomolecules, 2020 As a major polysaccharide component of the extracellular matrix, hyaluronan plays essential roles in the organization of tissue architecture and the regulation of cellular functions, such as cell proliferation and migration, through interactions with ...
Takashi Kobayashi +2 more
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Diagnostic usefulness of Hyaluronan and Hyaluronan Synthases-A Review [PDF]
International Journal of Multidisciplinary and Current Research, 2018 The first isolation of HA was in the year 1934, but research on HA and its clinical significance in health and disease started only in the year 1970. Both HA and HASs play a significant role in many physiological and pathological processes. The cellular HA synthesis are coordinated collectively by HASs.
Dr.Oviya Senthilraj +3 more
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Reproductive Biology and Endocrinology, 2022 Background Hyaluronan is the main component of the cumulus-oocyte complex (COC) matrix, and it maintains the basic structure of the COC during ovulation.
Hsun-Ming Chang +3 more
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Journal of Cancer Research and Clinical Oncology, 2022 Purpose Hyaluronan modulates tumour progression, including cell adhesion, cohesion, proliferation and invasion, and the cancer stem cell phenotype. In ovarian cancer, high levels of stromal hyaluronan are associated with poor prognosis.
Jette Riecks +6 more
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