Results 81 to 90 of about 181,818 (312)

Future directions for the management of pain in osteoarthritis. [PDF]

, 2014
Osteoarthritis (OA) is the predominant form of arthritis worldwide, resulting in a high degree of functional impairment and reduced quality of life owing to chronic pain. To date, there are no treatments that are known to modify disease progression of OA
Aigner T, Anasuya Kuttapitiya, Balanescu AR, Bannuru RR, Chou R, da Costa BR, Danielsson L, Fanelli A, Fransen M, Haviv B, Huskisson EC, Lim YZ, Mankin HJ, McAlindon TE, Merlotti D, Nguyen US, Nidhi Sofat, Pelletier JP, Sagar DR, Sellers RS, Sofat N, Tannenbaum H, Wajed J, Wakitani S   +23 more
core   +1 more source

Controlling Intestinal Organoid Polarity using Synthetic Dynamic Hydrogels Decorated with Laminin‐Derived IKVAV Peptides

Advanced Healthcare Materials, EarlyView.
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns, Joost A. P. M. Wijnakker, Victor A. Veenbrink, Riccardo Bellan, Fenna W. B. Craenmehr, Simone I. S. Hendrikse, Johnick F. van Sprang, Wim de Lau, E. W. Meijer, Hans Clevers, Patricia Y. W. Dankers   +10 more
wiley   +1 more source

Optimal conjugation of catechol group onto hyaluronic acid in coronary stent substrate coating for the prevention of restenosis

Journal of Tissue Engineering, 2016
Although endovascular stenting has been used as an interventional therapy to treat cardio- and cerebro-vascular diseases, it is associated with recurrent vascular diseases following stent thrombosis and in-stent restenosis.
Eugene Lih, Seul Gi Choi, Dong June Ahn, Yoon Ki Joung, Dong Keun Han   +4 more
doaj   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Synthesis and characterization of novel scaffold for bone tissue engineering based on Whartons´s jelly [PDF]

, 2017
A composite is a material made of more than one component, and the bond between the components is on a scale larger than the atomic scale. The objective of the present study was to synthesize and perform the structural characterization and biological ...
Aniket, Aniket, Bakhtiari, Barbeck, Boryskina, Cabrini, Camacho, Cao, Carlton, Chang, Desimone, Dhimolea, El-Ghannam, El-Ghannam, Fan, Fong, Franz, Ghanaati, Guo, Hanjaya-Putra, Heinemann, Hench, Hench, Hench, Hench, Henkel, Herten, Hutmacher, Kandamchira, Katti, Kikuchi, Kim, Kisiel, Klein, Lee, Letaief, Leu, Li, Li, Li, Libonati, Lin, Liu, Ma, MacDuff, Meng, Oonishi, Pek, Petite, Plewinski, Qian, Quinlan, Quinlan, Rodrigues, Roveri, Salgado, Salma-Ancane, Santos, Scalera, Schneider, Sha, Shin, Singh, Sionkowska, Sobolewski, Taghizadeh, Tamimi, Tapety, Twardowski, Vidal, Xu, Zhang   +71 more
core   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Exploring the Formulation and Approaches of Injectable Hydrogels Utilizing Hyaluronic Acid in Biomedical Uses

Advances in Pharmacological and Pharmaceutical Sciences
The characteristics of injectable hydrogels make them a prime contender for various biomedical applications. Hyaluronic acid is an essential component of the matrix surrounding the cells; moreover, hyaluronic acid’s structural and biochemical ...
Hadeia Mashaqbeh, Batool Al-Ghzawi, Fatima BaniAmer   +2 more
doaj   +1 more source

Management of complications associated with the use of hyaluronic acid fillers. Recommendations of the Aesthetic Dermatology Section of the Polish Dermatological Society

Przegląd Dermatologiczny, 2020
The most common treatments in the field of aesthetic dermatology and broadly understood aesthetic medicine are those with the use of fillers. For many, hyaluronic acid injections are considered very safe and the effects predictable. Therefore, the widely
Barbara Zegarska, Marcin Ambroziak, Małgorzata Ornatowska, Wioletta Barańska-Rybak   +3 more
doaj   +1 more source

3D Printing Strategies for Bioengineering Human Cornea

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in 3D bioprinting strategies for engineering human corneas. Key aspects include the replication of corneal transparency, curvature, and biomechanical properties, alongside innovations in recent advancements in 3D printing methods, which benefit in overcoming current challenges.
Yunong Yuan, Khoon S. Lim, Gerard Sutton, Gordon G. Wallace, Jingjing You   +4 more
wiley   +1 more source

Performance and Safety of Amino-Acid- and Hydroxyapatite Enriched-Hyaluronic Acid Intradermal Gel in Facial Skin Defects

Medicina
Background and Objectives: The facial skin defects associated with aging are common concerns in the aging population. Hyaluronic-acid-based intradermal gels have established themselves as safe and effective treatments for addressing these concerns ...
Salvatore Todde, Fabiano Svolacchia, Lorenzo Svolacchia, Federica Giuzio, Sameer Kumar Panda, Giuseppe A. Ferraro   +5 more
doaj   +1 more source