Results 11 to 20 of about 42,196 (203)

Molecular, immunological, and biological characterization of Tityus serrulatus venom hyaluronidase: new insights into its role in envenomation. [PDF]

PLoS Neglected Tropical Diseases, 2014
BACKGROUND: Scorpionism is a public health problem in Brazil, and Tityus serrulatus (Ts) is primarily responsible for severe accidents. The main toxic components of Ts venom are low-molecular-weight neurotoxins; however, the venom also contains poorly ...
Carolina Campolina Rebello Horta, Bárbara de Freitas Magalhães, Bárbara Bruna Ribeiro Oliveira-Mendes, Anderson Oliveira do Carmo, Clara Guerra Duarte, Liza Figueiredo Felicori, Ricardo Andrez Machado-de-Ávila, Carlos Chávez-Olórtegui, Evanguedes Kalapothakis   +8 more
doaj   +1 more source

Hyaluronidase Promote Transdermal Diffusion of Small Sized Curcumin Nanocrystal by Dissolving Microneedles Delivery

Pharmaceutics, 2023
Hyaluronidase is clinically used in treating many skin diseases due to its good permeability-promoting effect, which may motivate the diffusion and absorption of drugs. To verify the penetration osmotic effect of hyaluronidase in microneedles, 55 nm-size
Xiaoqing Miao, Jingru Zhao, Hong Xiang, Xiaoxi Shi   +3 more
doaj   +1 more source

Hyaluronidase: An overview of its properties, applications, and side effects

Archives of Plastic Surgery, 2020
Hyaluronidase, an enzyme that breaks down hyaluronic acid, has long been used to increase the absorption of drugs into tissue and to reduce tissue damage in cases of extravasation of a drug.
Hyunwook Jung
doaj   +1 more source

Allergic reactions to hyaluronidase in pain management -A report of three cases- [PDF]

Korean Journal of Anesthesiology, 2011
Hyaluronidase has been gaining interest because it reduces tissue edema and fibrosis. Although rare, hyaluronidase has been shown to cause allergic reactions.
Tae Wan Kim, Jae Hoon Lee, Kyung Bong Yoon, Duck Mi Yoon   +3 more
doaj   +1 more source

Synthesis and biological evaluations of oleanolic acid indole derivatives as hyaluronidase inhibitors with enhanced skin permeability

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Oleanolic acid (OA) is a natural cosmeceutical compound with various skin beneficial activities including inhibitory effect on hyaluronidase but the anti-hyaluronidase activity and mechanisms of action of its synthetic analogues remain unclear. Herein, a
Hao He, Huifang Li, Toyosi Akanji, Shengli Niu, Zhujun Luo, Dongli Li, Navindra P. Seeram, Panpan Wu, Hang Ma   +8 more
doaj   +1 more source

Optimization of hyaluronidase enzyme conditions produced from pseudomonas aerigenosa isolated from diabetic foot ulcer patients [PDF]

Journal of Medical and Life Science, 2023
Using clinically isolated pseudomonas aerigenosa, the best conditions for making hyaluronidase were studied. The production medium pH7 with 0.5% lactose and yeast extract, a novel bacterial culture (106Cell/ml), and 37oC for 24 hours produced the maximum
Furqan Kadhum
doaj   +1 more source

Toxicity of the recombinant human hyaluronidase ALT-BC4 on embryonic development

Journal of Animal Science and Technology, 2021
Cumulus-oocyte complexes (COCs), which contain immature oocytes, are matured in vitro for in vitro embryo production. Oocyte and cumulus cells are then separated using hyaluronidase.
Ji Hye Lee, Miyoun Yoo, Sang Mee Lee, Soon-Jae Park, Tae Young Kil, Min Kyu Kim   +5 more
doaj   +1 more source

Standardized in vitro analysis of the degradability of hyaluronic acid fillers by hyaluronidase

European Journal of Medical Research, 2018
Background Hyaluronidase is a hyaluronic acid (HA) metabolizing enzyme, which is approved as an adjuvant for infiltration anesthesia. The “off-label” use of hyaluronidase is regarded as gold standard for the management of HA-filler-associated ...
Bettina Alexandra Buhren, Holger Schrumpf, Edwin Bölke, Kai Kammers, Peter Arne Gerber   +4 more
doaj   +1 more source

Comparison of Efficacy and Safety of Subtenon’s Anaesthesia with and without Hyaluronidase in Bilateral Cataract Patients

Journal of Clinical and Biomedical Sciences, 2022
Background: The effect of subtenon’s block with the usage of hyaluronidase in terms of analgesia and akinesia was studied in different sets of people and the results were not satisfactory in all of them .This study eliminates bias and mitigates ...
Sai Monisha Jammula, T R Manjula , Mohan H Kumar   +2 more
doaj   +1 more source

Injected Hyaluronidase Reduces the Volume of Exogenous Hyaluronate Fillers in Mice and Results in Clinical Improvement in a Patient with Pretibial Myxedema

Dermatopathology, 2016
Background: Hyaluronidases are essential for the breakdown of hyaluronate (HA) in tissues and may be used to prevent the adverse effects of HA fillers.
Sébastien Menzinger, Aysin Kaya, Jean-Hilaire Saurat, Gürkan Kaya   +3 more
doaj   +1 more source