Results 21 to 30 of about 42,196 (203)

Pain Levels after Local Anaesthetic with or without Hyaluronidase in Carpal Tunnel Release: A Randomised Controlled Trial

Advances in Orthopedics, 2015
Purpose. Hyaluronidase is an enzyme that temporarily liquefies the interstitial barrier, allowing easy dispersal of local anaesthetic through cleavage of tissue planes.
G. Yeo, A. Gupta, G. Ding, H. Skerman, M. Khatun, D. Melsom   +5 more
doaj   +1 more source

Hyaluronidase of bloodsucking insects and its enhancing effect on leishmania infection in mice. [PDF]

PLoS Neglected Tropical Diseases, 2008
BACKGROUND: Salivary hyaluronidases have been described in a few bloodsucking arthropods. However, very little is known about the presence of this enzyme in various bloodsucking insects and no data are available on its effect on transmitted ...
Vera Volfova, Jitka Hostomska, Martin Cerny, Jan Votypka, Petr Volf   +4 more
doaj   +1 more source

Endothelial surface layer degradation by chronic hyaluronidase infusion induces proteinuria in apolipoprotein E-deficient mice. [PDF]

PLoS ONE, 2010
OBJECTIVE: Functional studies show that disruption of endothelial surface layer (ESL) is accompanied by enhanced sensitivity of the vasculature towards atherogenic stimuli. However, relevance of ESL disruption as causal mechanism for vascular dysfunction
Marijn C Meuwese, Lysette N Broekhuizen, Mayella Kuikhoven, Sylvia Heeneman, Esther Lutgens, Marion J J Gijbels, Max Nieuwdorp, Carine J Peutz, Erik S G Stroes, Hans Vink, Bernard M van den Berg   +10 more
doaj   +1 more source

Innovative insights on cleavage and hydrolysis mechanisms of hyaluronic acid: Opportunities and challenges in the preparation and application of hyaluronic acid and hyaluronidases

Carbohydrate Polymer Technologies and Applications
Hyaluronidase is used extensively across various domains, with food industry, healthcare, and surgical applications. Hyaluronidase produces low molecular weight hyaluronate through three mechanisms, substrate cleavage and two different hydrolysis ...
Panhong Yuan, Helin Li, Linjiang Zhu, Zonghui Song, Zhengsheng Pan, Xiaolong Chen   +5 more
doaj   +1 more source

Recombinant expression, purification and characterization of human hyaluronidases

, 2007
Hyaluronidases and their substrate, hyaluronic acid, are known to play a role in signal transduction events directly correlated with tumor growth and cell migration. Yet correlations with disease progression are controversial due to scarce information on
Hofinger, Edith
core   +1 more source

Effects of Hyaluronidase during In Vitro Maturation on Maturation and Developmental Competence in Porcine Oocytes

Journal of Animal Reproduction and Biotechnology, 2019
The aim of this study was to investigate effects of hyaluronidase during IVM on oocyte maturation, oxidative stress status, expression of cumulus expansion-related (PTX, pentraxin; GJA1, gap junction protein alpha 1; PTGS2, prostaglandin-endoperoxide ...
Ye-Eun Jeon, Yong Hwangbo, Hee-Tae Cheong, Choon-Keun Park   +3 more
doaj   +1 more source

Hyaluronidase facilitated subcutaneous immunoglobulin in primary immunodeficiency

, 2013
Stephen Jolles Department of Immunology, University Hospital of Wales, Cardiff, UK Abstract: Immunoglobulin (Ig)-replacement therapy represents the mainstay of treatment for patients with primary antibody deficiency and is administered either ...
Jolles S, Jolles, Stephen
core   +1 more source

Biochemical Isolation and Characterization of Hyaluronidase Enzyme from Venom of Egyptian Honey Bee Apis Mellifera Lamarckii

Journal of Apicultural Science, 2020
The hyaluronidase enzyme has been used in many such fields of medicine as ophthalmology, orthopaedia, internal medicine, gynecology, surgery, oncology and dermatology.
Abdel-Monsef Mohammed M., Zidan Hind A., Darwish Doaa A., Masoud Hassan M., Helmy Mohamed S., Ibrahim Mahmoud A.   +5 more
doaj   +1 more source

Hyaluronidase involvement in Streptococcus pneumoniae biofilm activity [PDF]

Streptococcus pneumoniae causes numerous severe infections and results in a significant number of mortality cases due to various virulence factors, including its ability to form a biofilm.
Enche Othman, Mohammad Izwan, Mohd Amin, Nor Munirah, Mohd Nayian, Nurul Azahana, Ahmad Suaidan, Muhammad Abdullah, Abu Mansor, Abu Zarrin, Ahmad Yusof @ Hanafi, Hanani   +5 more
core   +1 more source

Genotypic and Phenotypic Assessment of Hyaluronidase among Type Strains of a Select Group of Staphylococcal Species

International Journal of Microbiology, 2009
Hyaluronidases degrade hyaluronic acid, a major polysaccharide of the extracellular matrix of tissues, and are considered important for virulence in a number of Gram-positive and -negative bacteria.
Mark E. Hart, Morgan J. Hart, Anna J. Roop   +2 more
doaj   +1 more source