Results 71 to 80 of about 706 (250)

Design and Implementation of Approximate Hybrid Floating-Point Multipliers for Signal-Processing Applications

IEEE Access
Floating-point (FP) multipliers are critical components in high-performance computing systems, particularly in signal processing, graphics, and machine learning applications. However, traditional FP multipliers face challenges in power, area, and latency
B. S. Gurucharan, Anwesh Rao, B. S. Kariyappa   +2 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

MINI Logic 1-Bit Adder: A Comparison with Hybrid NMOS-Memristor-Logic Styles Using Ta2O5/Al2O3 Based RRAM Device

Advances in Electrical and Computer Engineering
This study addresses the demand for more efficient logic circuits by focusing on reducing area, power consumption, and delay. As conventional CMOS technology faces scaling and efficiency limitations, integrating emerging memory technologies like ...
NITHYA, N., PARAMASIVAM, K.
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Analysis of MTJ write circuits and design of hybrid MTJ/CMOS full adder for in-memory computation architecture

Cogent Engineering
Hybrid magnetic tunnel junction/complementary metal oxide semiconductor (MTJ/CMOS) in-memory computation (IMC) has emerged as a future computing architecture that mitigates the memory wall and energy wastage problems observed in the conventional von ...
Prashanth Barla, Ramya Moodakare
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Design of a low-power hybrid adder with reduced delay using a conditional algorithm-based behavioral model

Discover Electronics
This paper examines self-switching for the function of a full adder, a fundamental block used in building a circuit to count one’s circuit using a conditional algorithm.
Mohamed Sulaiman S., Dhandapani Vaithiyanathan, Sivakumar N., Britto Pari James   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

FPGA-Efficient Digital Implementation of a Multiplierless Cochlea–Neuron Interaction Model for Industrial-Scale Neural Systems

IEEE Open Journal of the Industrial Electronics Society
This article presents a novel digital design methodology for modeling cochlea–neuron interactions, tailored for applications within the scope of industrial electronics, such as real-time biosensing, smart health interfaces, and resource-aware ...
Songjie Xiang, Ru Chen, Die Yu, Hailing Liu, Mohammad Sh. Daoud, Guodao Zhang, Yanling Chu, Abdulilah Mohammad Mayet, Yideng Huang   +8 more
doaj   +1 more source