Results 91 to 100 of about 49,201 (297)

DNA in situ hybridization of individual colonies to determine lineage derivation in leukemia [PDF]

Leukemia, 1998
The degree of lineage commitment of the hematopoietic stem cell in chronic myelomonocytic leukemia (CMML) and in acute myelogenous leukemia (AML) remains debatable and may be heterogeneous depending on the patient subgroup. In this study, we have used a modification of DNA in situ hybridization which adapts this technique to the analysis of karyotype ...
R, Kurzrock, M, Talpaz, M, Beran, D, Harris, Z, Estrov   +4 more
openaire   +2 more sources

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

Advanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse, Mahtab Khodadadi, Kiran M. Ali, Suh Hee Cook, Bryson T. Proctor, Tanya Upadhyay, Daxian Zha, Fatema Tuj Jahura, Marziyeh Boosaliki, Jessica M. Gluck   +9 more
wiley   +1 more source

Phylogeny of beech in western Eurasia as inferred by approximate Bayesian computation

Acta Societatis Botanicorum Poloniae, 2018
The Fagus sylvatica L. species complex in Europe and Western Asia comprises two commonly recognized subspecies, F. sylvatica subsp. sylvatica [= F. sylvatica sensu stricto (s. str.)] and F. sylvatica subsp. orientalis (= F.
Dušan Gömöry, Ladislav Paule, Vladimír Mačejovský   +2 more
doaj   +1 more source

Early evolution in a hybrid swarm between outcrossing and selfing lineages in Geum [PDF]

Heredity, 2011
Although often considered as evolutionary dead ends, selfing taxa may make an important contribution to plant evolution through hybridization with related outcrossing lineages. However, there is a shortage of studies examining the evolutionary dynamics of hybridization between outcrossing and selfing taxa.
M, Ruhsam, P M, Hollingsworth, R A, Ennos   +2 more
openaire   +2 more sources

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Hybrid enrichment of adaptive variation revealed by genotype–environment associations in montane sedges

, 2022
The role of hybridization in diversification is complex and may result in many possible outcomes. Not only can hybridization produce new lineages, but those lineages may contain unique combinations of adaptive genetic variation derived from parental taxa
Massatti, Rob, Knowles, L. Lacey, Rob Massatti, Richard G. J. Hodel, Hodel, Richard G. J., L. Lacey Knowles   +5 more
core   +1 more source

Genetic diversity and genetic exchange in Trypanosoma cruzi: dual drug-resistant "progeny" from episomal transformants

Memorias do Instituto Oswaldo Cruz, 1999
Extensive characterisation of Trypanosoma cruzi by isoenzyme phenotypes has separated the species into three principal zymodeme groups, Z1, Z2 and Z3, and into many individual zymodemes. There is marked diversity within Z2.
JR Stothard, IA Frame, MA Miles
doaj   +1 more source

Segmental Translocation Contributed to the Origin of the Brassica S-locus

Horticultural Plant Journal, 2020
Self-incompatibility (SI), which has recurred during the evolution of plants, is one of the most important cross-pollination mating systems. Three S-loci have been reported in Brassicaceae, namely, Arabidopsis lyrata (Al), Brassica (Br), and ...
Yinan Cui, Mu Zhuang, Jian Wu, Jisheng Liu, Yiyue Zhang, Lingkui Zhang, Yile Huang, Xu Cai, Jianli Liang, Kang Zhang, Xiaowu Wang, Feng Cheng   +11 more
doaj   +1 more source

Coalescent Simulations Reveal Hybridization and Incomplete Lineage Sorting in Mediterranean Linaria

PLoS ONE, 2012
We examined the phylogenetic history of Linaria with special emphasis on the Mediterranean sect. Supinae (44 species). We revealed extensive highly supported incongruence among two nuclear (ITS, AGT1) and two plastid regions (rpl32-trnL(UAG), trnS-trnG).
Blanco Pastor, Jose Luis, Vargas, P., Pfeil, B.E.   +2 more
openaire   +5 more sources