Results 61 to 70 of about 1,491,122 (300)

Lineage tree analysis of immunoglobulin variable-region gene mutations in autoimmune diseases: chronic activation, normal selection [PDF]

open access: yes, 2006
Autoimmune diseases show high diversity in the affected organs, clinical manifestations and disease dynamics. Yet they all share common features, such as the ectopic germinal centers found in many affected tissues.
Neta S. Zuckerman   +29 more
core   +1 more source

Lineage-defining missense mutations in S. Paratyphi A genomes.

open access: yes, 2023
Lineage-defining missense mutations in S. Paratyphi A genomes.
Monisha Priya Teekaraman (15374729)   +29 more
core   +1 more source

Distinct hybridization modes in wide- and narrow-ranged lineages of Causonis (Vitaceae)

open access: yesBMC Biology, 2023
Abstract Background Explaining contrasting patterns of distribution between related species is crucial for understanding the dynamics of biodiversity. Despite instances where hybridization and whole genome duplication (WGD) can yield detrimental outcomes, a role in facilitating the expansion of distribution range has ...
Yu, J   +14 more
openaire   +4 more sources

Ancient hybridization inCurcuma(Zingiberaceae)—Accelerator or brake in lineage diversifications?

open access: yesThe Plant Journal, 2023
SUMMARYHybridization is a widespread phenomenon in the evolution of plants and exploring its role is crucial to understanding diversification processes of many taxonomic groups. Recently, more attention is focused on the role of ancient hybridization that has repeatedly been shown as triggers of evolutionary radiation, although in some cases, it can ...
Jana Skopalíková   +10 more
openaire   +2 more sources

Molecular characterization and expression analysis of SYCP1 and SYCP3 in hybrid fish derived from Megalobrama amblycephala × Culter alburnus

open access: yesJournal of the World Aquaculture Society
SYCP1 and SYCP3 are essential testis‐specific genes for centromere pairing during meiosis, as well as for spermatogenesis and fertility in male germ cells.
Jia Xu   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

No evidence of a hybrid origin of the ashy‐throated parrotbill Sinosuthora alphonsiana

open access: yesJournal of Avian Biology, 2023
This mini‐review is dedicated to a critical re‐appraisal of the putative hybrid origin of the grey‐cheeked populations of the ashy‐throated parrotbill Sinosuthora alphonsiana that was postulated based on the results of a clustering analysis using a set ...
Martin Päckert
doaj   +1 more source

Unveiling current Guanaco distribution in chile based upon niche structure of phylogeographic lineages: Andean puna to subpolar forests. [PDF]

open access: yesPLoS ONE, 2013
Niche description and differentiation at broad geographic scales have been recent major topics in ecology and evolution. Describing the environmental niche structure of sister taxa with known evolutionary trajectories stands out as a useful exercise in ...
Benito A González   +3 more
doaj   +1 more source

Hybrid lineages of CD4+ T cells: a handbook update

open access: yesFrontiers in Immunology
CD4+ T lymphocytes have been classified into several lineages, according to their gene expression profiles and their effector responses. Interestingly, recent evidence is showing that many lineages could yield hybrid phenotypes with unique properties and functions.
Antonio Bensussen   +4 more
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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