Results 41 to 50 of about 524,580 (264)
Challenges and Solutions of Applying Large-Scale Agile at Organization-al Level [PDF]
Large-scale agile development receives widespread interest today in research and practice. Two different dimensions could be considered in the context of applying agile at large-scale: individual level, like project or team, and organization level.
Florin DUMITRIU +2 more
doaj +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Seepage is one of the most challenging issues in some procedures such as design, construction, and operation of embankment or earth fill dams. The purpose of this research is to develop a new solution based on governing equations to solve the seepage ...
Dongchun Tang +6 more
doaj +1 more source
Hybrid method of tolerance design [PDF]
A new method of tolerance design, which we call the hybrid method that accelerates the attainment of optimal design center, is proposed. The method combines geometry search with statistical process. At the start of the process, the region of acceptability is estimated using boundary search method, A new tolerance region that covers much of the ...
Foo, Say Wei, Lin, Yu
openaire +2 more sources
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
In this article, we comprehensively assessed the newly released long-term high-spatial-resolution Global LAnd Surface Satellite (GLASS) surface longwave (LW) radiation product using site measurements of LW fluxes. In total, three years of ground-measured
Qi Zeng, Jie Cheng, Lixin Dong
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Hybrid Method for Full-Wave Simulations of Forests at L-Band
The full-wave simulations of 3D Maxwell equations of forests at L-band are carried out with a two-step hybrid method. The tallest trees considered include one 8-meter tall trunk, 18 primary branches and 108 secondary branches.
Weihui Gu +3 more
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
IMPACT OF PANELISTS ON WIBOR RATES – HYBRID APPROACH
The reform of financial benchmarks is one of the key elements of stability and trust in the financial market. In the money market, it is difficult to implement reforms because of the disappearance of the interbank deposit market, which was a reference ...
Piotr Mielus
doaj +1 more source

