Results 41 to 50 of about 530,036 (269)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A comparative framework to develop transferable species distribution models for animal telemetry data

open access: yesEcosphere
Species distribution models (SDMs) have become increasingly popular for making ecological inferences, as well as predictions to inform conservation and management.
Joshua A. Cullen   +8 more
doaj   +1 more source

FORECASTING THE NUMBER OF ASEAN TOURISTS TO INDONESIA WITH THE HYBRID SINGULAR SPECTRUM ANALYSIS-SUPPORT VECTOR MACHINE METHOD [PDF]

open access: yesGeo Journal of Tourism and Geosites
Tourism plays a crucial role in Indonesia's economy, significantly contributing to the nation’s revenue, employment, and overall growth. ASEAN countries represent one of the largest sources of international tourists, making their travel patterns ...
Gracia Joanne Crissan Br HUTABARAT*   +2 more
doaj   +1 more source

Hybrid model of content extraction

open access: yesJournal of Computer and System Sciences, 2012
AbstractWe present a hybrid model for content extraction from HTML documents. The model operates on Document Object Model (DOM) tree of the corresponding HTML document. It evaluates each tree node and associated statistical features like link density and text distribution across the node to predict significance of the node towards overall content ...
Qureshi, Pir Abdul Rasool   +1 more
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The Use of Data Mining Techniques in Predicting the Noise Emitted By the Trailing Edge of Aerodynamic Objects

open access: yesJOIV: International Journal on Informatics Visualization, 2019
Aerodynamic is a branch of fluid dynamics that evaluates the behavior of airflow and its interaction with moving objects. The most important application of aerodynamic is in aerospace engineering, designing and construction of flying objects.
Abdusalam Shaltooki, Mojtaba Jamshidi
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Spatio-Temporal Feature Extraction for Pipeline Leak Detection in Smart Cities Using Acoustic Emission Signals: A One-Dimensional Hybrid Convolutional Neural Network–Long Short-Term Memory Approach

open access: yesApplied Sciences
Pipeline leakage represents a critical challenge in smart cities and various industries, leading to severe economic, environmental, and safety consequences.
Saif Ullah   +4 more
doaj   +1 more source

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