Results 81 to 90 of about 2,269,400 (346)

OpenCL + OpenSHMEM Hybrid Programming Model for the Adapteva Epiphany Architecture

open access: yes, 2016
There is interest in exploring hybrid OpenSHMEM + X programming models to extend the applicability of the OpenSHMEM interface to more hardware architectures.
D Wentzlaff, J Ross, JE Stone, M Baker
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A Dual-Decomposition Graph-Mamba-Transformer Framework for Ultra-Short-Term Wind Power Forecasting

open access: yesApplied Sciences
Accurate ultra-short-term wind power forecasting is vital for the secure and economic operation of power systems with high renewable penetration. Conventional models, however, struggle with multi-scale frequency feature extraction, dynamic cross-variable
Jinming Gao   +4 more
doaj   +1 more source

Microgrid - The microthreaded many-core architecture [PDF]

open access: yes, 2013
Traditional processors use the von Neumann execution model, some other processors in the past have used the dataflow execution model. A combination of von Neuman model and dataflow model is also tried in the past and the resultant model is referred as ...
Uddin, Irfan
core  

Hybrid plasma modeling. [PDF]

open access: yes, 2009
This report summarizes the work completed during FY2007 and FY2008 for the LDRD project ''Hybrid Plasma Modeling''. The goal of this project was to develop hybrid methods to model plasmas across the non-continuum-to-continuum collisionality spectrum. The primary methodology to span these regimes was to couple a kinetic method (e.g., Particle-In-Cell ...
Hopkins, Matthew Morgan   +3 more
openaire   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Hybrid Modeling of Plasmas [PDF]

open access: yes, 2010
5 pages, LaTeX; Submitted to the Proceedings of the 8th European Conference on Numerical Mathematics and Advanced Applications, 2009; Small language ...
openaire   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen   +10 more
wiley   +1 more source

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