Results 51 to 60 of about 528,030 (250)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Interface localized modes and hybrid lattice solitons in waveguide arrays

open access: yes, 2006
We discuss the formation of guided modes localized at the interface separat- ing two different periodic photonic lattices. Employing the effective discrete model, we analyze linear and nonlinear interface modes and also predict the existence of stable ...
Garanovich   +10 more
core   +2 more sources

$I=2$ $\pi\pi$ potential in the HAL QCD method with all-to-all propagators [PDF]

open access: yes, 2014
In this paper, we perform the first application of the hybrid method (exact low modes plus stochastically estimated high modes) for all-to-all propagators to the HAL QCD method.
Akahoshi, Yutaro   +5 more
core   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The Decay Properties of the 1^{-+} Hybrid State

open access: yes, 2011
Within the framework of the QCD sum rules, we consider the three-point correlation function, work at the limit q^2 -> 0 and m_\pi -> 0, and pick out the singular term ~ {1\over q^2} to extract the pionic coupling constants of the 1^{-+} hybrid meson ...
A. A. Ovchinnikov   +7 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Observation of enhanced spontaneous and stimulated emission of GaAs/AlGaAs nanowire via the Purcell effect

open access: yesAIP Advances, 2015
We experimentally demonstrated enhanced spontaneous and stimulated emission of GaAs/AlGaAs nanowire via the Purcell effect. By integrating the NW and SiO2-Au substrate, the hybridization of the dielectric modes in the NW with surface plasmons on the ...
Wei Wei, Xia Zhang, Xin Yan, Xiaomin Ren
doaj   +1 more source

Electro-opto-mechanical radio-frequency oscillator driven by guided acoustic waves in standard single-mode fiber

open access: yes, 2017
An opto-electronic radio-frequency oscillator that is based on forward scattering by the guided acoustic modes of a standard single-mode optical fiber is proposed and demonstrated.
Diamandi, Hilel Hagai   +2 more
core   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Molecular optomechanics in the anharmonic cavity-QED regime using hybrid metal-dielectric cavity modes

open access: yes, 2019
Using carefully designed hybrid metal-dielectric resonators, we study molecular optomechanics in the strong coupling regime ($g_{\rm }^2/\omega_m {>} \kappa$), which manifests in anharmonic emission lines in the sideband-resolved region of the cavity ...
Dezfouli, Mohsen Kamandar   +2 more
core   +1 more source

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