Results 61 to 70 of about 1,050,112 (246)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Research on Hybrid Multi-Attribute Three-Way Group Decision Making Based on Improved VIKOR Model

Mathematics, 2022
In the era of internet connection and IOT, data-driven decision-making has become a new trend of decision-making and shows the characteristics of multi-granularity.
Jiekun Song, Zeguo He, Lina Jiang, Zhicheng Liu, Xueli Leng   +4 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

On Higher-Order Generalized Fibonacci Hybrinomials: New Properties, Recurrence Relations and Matrix Representations

Mathematics
This paper presents a comprehensive survey of the generalization of hybrid numbers and hybrid polynomials, particularly in the fields of mathematics and physics.
Can Kızılateş, Wei-Shih Du, Nazlıhan Terzioğlu   +2 more
doaj   +1 more source

Mass Predictions of Open-Flavour Hybrid Mesons from QCD Sum Rules

, 2016
Within QCD, colourless states may be constructed corresponding to exotic matter outside of the traditional quark model. Experiments have recently observed tetraquark and pentaquark states, but no definitive hybrid meson signals have been observed.
Harnett, Derek, Ho, Jason, Steele, Tom
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Solid-Fuel Regression Rate for Standard-Flow Hybrid Rocket Motors

Journal of Thermal Science and Technology, 2012
Marxman's diffusion-limited analysis of hybrid rocket combustion has been often used to investigate various combustion problems in hybrid rocket motors.
Takakazu MORITA, Saburo YUASA, Shigeru YAMAGUCHI, Toru SHIMADA   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Differentiation of mouse embryonic stem cells and their hybrids during embryoid body formation

Genetics and Molecular Biology, 2002
We studied the karyotypes of three hybrid clones of mouse embryonic stem cells and murine splenocytes (two having near diploid and one having near tetraploid chromosome numbers) and the characteristics of their differentiation during the formation of ...
Josane Mittmann, Irina Kerkis, Cinthia Kawashima, Marina Sukoyan, Enrico Santos, Alexandre Kerkis   +5 more
doaj   +1 more source

Thermodynamic simulation of a wind turbine-fuel cell hybrid system with application in a distributed generation system [PDF]

مجله مدل سازی در مهندسی, 2018
The aim of this article is to design wind turbine PEM (polymer electrolyte membrane) fuel cell hybrid system in standalone area for Tehran, Mashhad, Manjil, and Zabol.
جاماسب پیرکندی, Reza Harbi
doaj   +1 more source