Results 71 to 80 of about 2,685,895 (283)

A Note on Generalized k-Order F&L Hybrinomials

open access: yesAxioms
In this study, we introduce generalized k-order Fibonacci and Lucas (F&L) polynomials that allow the derivation of well-known polynomial and integer sequences such as the sequences of k-order Pell polynomials, k-order Jacobsthal polynomials and k-order ...
Süleyman Aydınyüz   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Hybrid numbers with balancing and Lucas balancing hybrid number coefficients

open access: yesCommunications Faculty of Sciences University of Ankara Series A1 Mathematics and Statistics
In this note, we made a connection between hybrid numbers and hybrid balancing, and hybrid Lucas balancing number. Initially, we obtained for these new number recurrence relation, some important relations among new numbers, and Binet's like formula.
Murat Turan   +1 more
openaire   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Hybrid numbers with the view of multiplicative calculus

open access: yesKuwait Journal of Science
This paper defines a new number system called multiplicative hybrid numbers. A multiplicative hybrid number is one that satisfies the non-commutative multiplication criteria using any combination of multiplicative complex (𝑖 2⋆ ⋆ = −⋆1⋆ ), multiplicative
Umut Selvi, Derya Sağlam, Emel Karaca
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

On complex hybrid numbers: Algebraic structures, matrix representations, and geometric interpretations

open access: yesKuwait Journal of Science
This work introduces complex hybrid numbers, an extension of hybrid numbers, which are defined as Z = z0 + z1i + z2ɛ + z3ℎ where zi are complex numbers and iℎ = −ℎi = i + ɛ.
Furkan Seçgin   +2 more
doaj   +1 more source

More identities on Fibonacci and Lucas hybrid numbers

open access: yes, 2021
WOS:000665848000017We give several identities about Fibonacci and Lucas hybrid numbers. We introduce the Fibonacci and Lucas hybrid numbers with negative subscripts.
Yılmaz, Nazmiye
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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