Results 51 to 60 of about 587,812 (219)

Simulation and experimental study of local high frequency resistance distribution in proton exchange membrane fuel cells under steady and dynamic conditions

Heliyon
Proton-exchange membrane (PEM) dry–wet variation during PEM fuel cell (PEMFC) operation markedly affects PEMFC lifespan. Therefore, deeper insights into the mechanical degradation mechanism of PEM require analysis of the membrane dry–wet change process ...
Xin Zhan, Jiaqi Sun, Feng Ding, Xiaozhi Xu, Wei Song, Zhigang Shao   +5 more
doaj   +1 more source

OPTIMAL ROUTE DEFINITION IN THE RAILWAY INFORMATION NETWORK USING NEURAL-FUZZY MODELS

Nauka ta progres transportu, 2019
Purpose. Modern algorithms for choosing the shortest route, for example, the Bellman-Ford and Dijkstra algorithms, which are currently widely used in existing routing protocols (RIP, OSPF), do not always lead to an effective result. Therefore, there is a
V. M. Pakhomova, Y. S. Mandybura
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Optimum Sizing Algorithm for An Off Grid Plant Considering Renewable Potentials and Load Profile

International Journal of Renewable Energy Development, 2017
The energy demand in remote area cannot be satisfied unless renewable energy based plants are locally installed. In order to be efficient, such projects should be sized on the basis of maximizing the renewable energies exploitation and meeting the ...
Nabiha Brahmi, Sana Charfi, Maher Chaabene   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Influence of SiC particle size on microstructure evolution and tribological behavior of CoCrFeNiAl coatings prepared by laser cladding

Journal of Materials Research and Technology
To investigate the influence of SiC particle size on the microstructure and tribological performance of high-entropy alloy (HEA) coatings, CoCrFeNiAl-based composite coatings were fabricated by laser cladding using SiC particles of three distinct size ...
Haoran Zhang, Yang Gao, Yaowei Yong, Lin Liu, Xiaoqiang Ren   +4 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Analysis of State-of-Charge Estimation Methods for Li-Ion Batteries Considering Wide Temperature Range

Energies
Lithium-ion batteries are the core energy storage technology for electric vehicles and energy storage systems. Accurate state-of-charge (SOC) estimation is critical for optimizing battery performance, ensuring safety, and predicting battery lifetime ...
Yu Miao, Yang Gao, Xinyue Liu, Yuan Liang, Lin Liu   +4 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source