Results 51 to 60 of about 2,377,753 (298)
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Wolf Kohn +3 more
openaire +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Hybrid systems are heterogenous dynamical systems characterized by interacting continuous and discrete dynamics. Such mathematical models have proved fruitful in a great diversity of engineering applications, including air-traffic control, automated manufacturing, and chemical process control.
Davoren, Jennifer M., Nerode, Anil
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The structure, chemical composition, thermal stability, and abuse responses of cathode materials are critical to the safety and economy of lithium-ion batteries (LIBs).
Yanru Yang +4 more
doaj +1 more source
Hybridity in MT: experiments on the Europarl corpus [PDF]
(Way & Gough, 2005) demonstrate that their Marker-based EBMT system is capable of outperforming a word-based SMT system trained on reasonably large data sets.
Groves, Declan, Way, Andy
core +1 more source
A bidirectional fluorescent two-hybrid system for monitoring protein–protein interactions
Two-hybrid systems have been the cornerstone of research into protein–protein interactions, but these systems typically rely on life/death reporters that put additional selective pressure on the host organism, and potentially lead to false positives ...
Nordgren, Ida Karin, Tavassoli, Ali
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Statistical ensembles in Hamiltonian formulation of hybrid quantum-classical systems
General statistical ensembles in the Hamiltonian formulation of hybrid quantum-classical systems are analyzed. It is argued that arbitrary probability densities on the hybrid phase space must be considered as the class of possible physically ...
Buric, N. +4 more
core +1 more source

