Results 71 to 80 of about 45,642,631 (346)
An algebra of hybrid systems [PDF]
The Journal of Logic and Algebraic Programming, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Höfner, Peter, Möller, Bernhard
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Optimization of hybrid PV-wind system: Case study Al-Tafilah cement factory, Jordan
, 2018 Hybrid power systems provide cost-effective utilization of renewable energy but depend on the geographic location due to the variability of solar and wind resources.
Al-Ghussain, Loiy +2 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Towards an Ultra Sensitive Hybrid Mass Sensor Based on Mode Localization without Resonance Tracking
Sensors, 2020 We present a mode localized mass sensor prototype based on a hybrid system excited at a fixed frequency slightly below the resonances. Indeed, we show, both theoretically and experimentally, that this condition yields higher sensitivities and similar ...
Claude Humbert +3 more
doaj +1 more source
Verification of Hybrid Systems [PDF]
, 2007 Embedded digital systems have become ubiquitous in everyday life. Many such systems, including many of the safety-critical ones, operate within or comprise tightly coupled networks of both discrete-state and continuous-state components. The behavior of such hybrid discrete-continuous systems cannot be fully understood without explicitly modeling and ...
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 2017 Environmental and economic impacts of the fertilizer drawn forward osmosis (FDFO) and nanofiltration (NF) hybrid system were conducted and compared with conventional reverse osmosis (RO) hybrid scenarios using microfiltration (MF) or ultrafiltration (UF)
Jung Eun Kim +7 more
semanticscholar +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Fabrication of Functionally Graded Materials Using Aluminum Alloys via Hot Extrusion
Metals, 2019 In this study, we have attempted to manufacture functionally graded materials (FGMs) using aluminum alloys 3003 and 6063 via a hot extrusion process to realize multifunctionality through achieving high strength and low weight.
Dasom Kim +6 more
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