Results 51 to 60 of about 936,481 (343)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Cahiers du MIMMOC, 2007 This article is divided into three parts. The first part offers a record of scientific works using hybridity. The second part explores the criticisms aimed at that concept. Finally the third part offers an extension of the debate on hybridity.
Nadia Kiwan
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Hybridity in Cultural Globalization [PDF]
, 2002 Hybridity has become a master trope across many spheres of cultural research, theory, and criticism, and one of the most widely used and criticized concepts in postcolonial theory.
Kraidy, Marwan M
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Hybrid Geometric Reduction of Hybrid Systems [PDF]
Proceedings of the 45th IEEE Conference on Decision and Control, 2006 This paper presents a unifying framework in which to carry out the hybrid geometric reduction of hybrid systems, generalizing classical reduction to a hybrid setting.
Ames, Aaron D., Sastry, Shankar
openaire +3 more sources
HYBRIDITY IN ALVAREZ’S AND SANTIAGO’S LITERATURE AND THE STRUGGLE FOR SELF-IDENTIFICATION
گۆڤارا زانستێن مرۆڤایەتی یا زانكۆیا زاخۆThis article elaborates on how hybridity is experienced and narrated under the conditions of exile through a critical engagement with Julia Alvarez’s How the García Girls Lost Their Accents (1991) and Esmeralda Santiago’s When I Was Puerto Rican (1993).
Dereen Moayed Tayeb, Lolav Alhamid
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source