Results 81 to 90 of about 538,227 (269)

EVOLUSI, SPESIASI, DAN HIBRIDISASI PADA BEBERAPA ANGGOTA SAPINDACEAE

open access: yesBioedukasi: Jurnal Pendidikan Biologi, 2012
Evolution in Sapindaceae have been running for a long time, as evidenced by the fossil of Sapindopsis encountered in the mid Cretaceous. Based on its characteris­tics, the genus is thought to live in stressful environments. Sapindaceae has the habitus of
Nina Ratna Djuita
doaj   +1 more source

A Hybrid Denotational Semantics for Hybrid Systems [PDF]

open access: yes, 2008
In this article, we present a model and a denotational semantics for hybrid systems. Our model is designed to be used for the verification of large, existing embedded applications. The discrete part is modeled by a program written in an extension of an imperative language and the continuous part is modeled by differential equations.
Olivier Bouissou, Matthieu Martel
openaire   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Epistasis, core-genome disharmony, and adaptation in recombining bacteria

open access: yesmBio
Recombination of short DNA fragments via horizontal gene transfer (HGT) can introduce beneficial alleles, create genomic disharmony through negative epistasis, and create adaptive gene combinations through positive epistasis.
Aidan J. Taylor   +22 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

DREAMS AND REALITY OF THE ACADEMICIAN I.G. KALINENKO IN CREATION OF DURUM WINTER WHEAT

open access: yesЗерновое хозяйство России, 2018
The article gives the analysis of 40-years selection activity of the academician I.G. Kalinenko in creation of the own initial material and the varieties of turgid and durum wheat which was new for the conditions of the Rostov region.
N. E. Samofalova
doaj  

Water-soaking effect and influence of nanoclay on mechanical properties of bamboo/glass fiber reinforced epoxy hybrid composites

open access: yesCogent Engineering
Fiber-reinforced polymer composites (FRPs) experience exposure to diverse environments throughout their intended design life. Investigating the aging process of FRPs immersed in water is crucial for enhancing the material’s durability.
Syed Mansoor Ahmad   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

MSAO-EDA: A Modified Snow Ablation Optimizer by Hybridizing with Estimation of Distribution Algorithm

open access: yesBiomimetics
Metaheuristic algorithms provide reliable and effective methods for solving challenging optimization problems. The snow ablation algorithm (SAO) performs favorably as a physics-based metaheuristic algorithm. Nevertheless, SAO has some shortcomings.
Wuke Li   +2 more
doaj   +1 more source

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