Results 61 to 70 of about 538,227 (269)

Methodological Problems and Strategic Goals of the Work on Creation of the Theory and Technology of New Generation Intelligent Computer Systems

open access: yesЦифровая трансформация
The main methodological problems and strategic goals of work on creating the theory and technology of intelligent computer systems of a new generation are considered.
V. V. Golenkov   +2 more
doaj   +1 more source

A survey on the studies employing machine learning (ML) for enhancing artificial bee colony (ABC) optimization algorithm

open access: yesCogent Engineering, 2020
Nature-inspired optimization (NIO) algorithms have gained quite a popularity among the researchers due to their good performance on difficult optimization problems.
Dervis Karaboga   +2 more
doaj   +1 more source

Hunting behavior and feeding ecology of Mojave rattlesnakes (Crotalus scutulatus), prairie rattlesnakes (Crotalus viridis), and their hybrids in southwestern New Mexico

open access: yesEcology and Evolution, 2023
Predators must contend with numerous challenges to successfully find and subjugate prey. Complex traits related to hunting are partially controlled by a large number of co‐evolved genes, which may be disrupted in hybrids.
Dylan W. Maag   +6 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Membrana metropolitana costera. Estrategias para proyectar una ciudad híbrida

open access: yesArea
Muchas de nuestras ciudades latinoamericanas se caracterizan por ser espacios fragmentados en continua expansión, no sólo en términos urbanos, sino también en lo social, económico y político.
Luisa Acosta Scandela   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Anthropogenic Hybridization Contributes to the Naturalization of Introduced Domestic Mallards (Anas platyrhynchos) at the Expense of Native New Zealand Gray Ducks (A. s. superciliosa)

open access: yesEcology and Evolution
Anthropogenically mediated hybridization can lead to several outcomes, with the most severe being hybrid swarms and the genetic extirpation of local populations.
Joshua I. Brown   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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