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Comparative Genomic and Transcriptomic Analysis Reveals Why Paenarthrobacter Strains Are Specialists in the Degradation of the Fungicide Iprodione. [PDF]
Michelioudakis V +7 more
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A promising dual catalytic "Isothiourea + X" platform: from classic ionic to radical transformations. [PDF]
Zhang B, Li Y, Ji Z, Wang J.
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Telomeric DNA damage landscapes distinguish oxidative from inflammatory cellular stress. [PDF]
Fleming AM, Burrows CJ.
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Combinatorial chemistry of hydantoins
Bioorganic & Medicinal Chemistry Letters, 1998Access to combinatorial chemistry of hydantoins is provided by convenient and versatile methods for the solid phase synthesis of libraries of 3,5-, 1,3- and 1,3,5-substituted hydantoins. The preparation of trisubstituted hydantoins features a Mitsunobu reaction for introduction of the substituent on N-1.
Boeijen, A. +2 more
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Hydantoins as antitumor agents
Journal of Medicinal Chemistry, 1977A series of 27 hydantoins was prepared and tested as antitumor agents. These were variously substituted in the 5 position but with special emphasis on the substituents (chloro, acetyl, chloroacetyl, and methyl) in the 1 and/or 3 positions. The most active compound was 5,5-bis(4-chlorophenyl)-1,3-dichlorohydantoin with a T/C value of 190% against P-388 ...
T R, Rodgers +3 more
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Microchemical tests for hydantoins and barbiturate-hydantoin mixtures
Microchemical Journal, 1972Abstract Substituted hydantoins, a number of which possess anticonvulsant activity and are prescribed alone or compounded with barbiturates, were observed to enter into a number of reactions commonly utilized to identify barbituric acid derivatives. The reactivity of the hydantoins with the Dille-Koppanyi and the Zwikker tests is sufficiently similar
Edward F. Rhodes, John I. Thornton
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SELENIUM-CONTAINING HYDANTOINS
Phosphorus and Sulfur and the Related Elements, 1988Abstract The influence of the exo-chalcogen atoms on the hydantoin skeleton of the complete series of molecules NH C(=X) NH C(=Y)CMe2 (X, Y = O, S, Se) has been studied from several points of view.
F. A. Devillanova +2 more
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The Journal of Pediatrics, 1975
Five unrelated children born to epileptic women treated with hydantoin anticonvulsants were found to have a similar broad multi-system pattern of abnormalities, including craniofacial anomalies, nail and digital hypoplasia, prenatal-onset growth deficiency, and mental deficiency.
J W, Hanson, D W, Smith
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Five unrelated children born to epileptic women treated with hydantoin anticonvulsants were found to have a similar broad multi-system pattern of abnormalities, including craniofacial anomalies, nail and digital hypoplasia, prenatal-onset growth deficiency, and mental deficiency.
J W, Hanson, D W, Smith
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Chinoide HydantoinâFarbstoffe
Justus Liebigs Annalen der Chemie, 1963AbstractHydantoine vom Typ I lassen sich mit PbO2 zu chinoiden Farbstoffen (II) dehydrieren. Aus der Dimethylaminoverbindung IV wurde das Betain V in roten Kristallen erhalten.
Kuhn, R., Blau, W.
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