Results 91 to 100 of about 1,978 (203)

A comparative study of the cis and trans isomers of two hydantoin compounds with anticonvulsant potency

Current Research in Biotechnology
Hydantoins are a class of compounds renowned for their diverse medical applications, particularly in neurology. Phenytoin (Dilantin) is one of the most well-known hydantoins, primarily used to stabilize neuronal membranes and prevent the spread of ...
Jana Tchekalarova, Tsveta Stoyanova, Petar Todorov   +2 more
doaj   +1 more source

Preservatives in Leave‐On Cosmetics Available on the Dutch Market

Contact Dermatitis, Volume 94, Issue 5, Page 541-544, May 2026.
Anton C. de Groot, Norbertus A. Ipenburg, Thomas Rustemeyer   +2 more
wiley   +1 more source

Efflux pump blockers in Gram-negative bacteria:The new generation of hydantoin based-modulators to improve antibiotic activity

Frontiers in Microbiology, 2016
Multidrug resistant (MDR) bacteria are an increasing health problem with the shortage of new active antibiotic agents. Among effective mechanisms that contribute to the spread of MDR Gram-negative bacteria are drug efflux pumps that expel clinically ...
Ewa eOtrębska-Machaj, Ewa eOtrębska-Machaj, Jacqueline eChevalier, Jadwiga eHandzlik, Ewa eSzymańska, Jakub eSchabikowski, Gérard eBoyer, Jean-Michel eBolla, Katarzyna eKieć-Kononowicz, Jean-Marie ePAGES, Sandrine eAlibert   +10 more
doaj   +1 more source

Hydantoins Derived from Ketopinic and 4-camphorcarboxylic Acids

, 2013
Diastereospecific formation of hydantoins from ketopinic and 4-camphorcarboxylic acids under Bucherer-Bergs reaction conditions has been investigated.
Voitenko, Zoia, Knizhnikov, Volodymyr, Gorichko, Marian   +2 more
core  

Solvent effects on the structure-property relationship of anticonvulsant hydantoin derivatives: A solvatochromic analysis

Chemistry Central Journal, 2011
Considering the pharmaceutical importance of hydantoins, a set of 25 derivatives of phenytoin, nirvanol and 5-methyl-5-phenylhydantoin, the lipophilicities of which were gradually increased by the introduction of different alkyl, cycloalkyl and alkenyl ...
Trišović Nemanja, Valentić Nataša, Ušćumlić Gordana   +2 more
doaj   +1 more source

Antinociceptive Effect of Hydantoin 3-Phenyl-5-(4-ethylphenyl)-imidazolidine-2,4-dione in Mice

Molecules, 2015
Imidazolidine derivatives, or hydantoins, are synthetic compounds with different therapeutic applications. Many imidazolidine derivatives have psychopharmacological properties, such as phenytoin, famous for its anticonvulsant efficacy, but also effective
Ronaldo Bezerra de Queiroz, Fabíola Lélis de Carvalho, Diogo Vilar da Fonsêca, José Maria Barbosa-Filho, Paula Regina Rodrigues Salgado, Luciano Leite Paulo, Ana Bárbara Maroja de Queiroz, Liana Clébia de Morais Pordeus, Severino Araújo de Souza, Helivaldo Diogenes da Silva Souza, Bruno Freitas Lira, Petrônio Filgueiras de Athayde-Filho   +11 more
doaj   +1 more source

Mechanism, kinetics and selectivity of selenocyclization of 5-alkenylhydantoins: an experimental and computational study

Beilstein Journal of Organic Chemistry, 2015
The mechanism and selectivity of a bicyclic hydantoin formation by selenium-induced cyclization are investigated. The proposed mechanism involves the intermediates formed by an electrophilic addition of the selenium reagent on a double bond of the ...
Biljana M. Šmit, Radoslav Z. Pavlović, Dejan A. Milenković, Zoran S. Marković   +3 more
doaj   +1 more source

Direct Cu-catalyzed N3-arylation of hydantoins

, 2019
A regioselective method for the N3-arylation of hydantoins is investigated. It constitutes an important development complementing classical cyclization strategies.
Peletis, Georgios
core  

Palladium-catalysed asymmetric allylic alkylation of hydantoins using bench-stable chiral palladium precatalysts. [PDF]

Hydantoins are important heterocyclic scaffolds present in a number of pharmaceutically relevant compounds. We report here a practical, scalable and enantioselective Pd-catalyzed asymmetric allylic alkylation (Pd-AAA) approach to diversely substituted ...
Jean, A, Leitch, DC, Clark, P, Keenan, T, Ma, Y-R, Huang, J, Liu, S, Hasija, A, Arseniyadis, S, Huang, P-Q   +9 more
core   +1 more source

Microwave-Mediated Intramolecular Carbanilide Cyclization to Hydantoins Employing Barium Hydroxide Catalysis

, 2016
Microwave-Mediated Intramolecular Carbanilide Cyclization to Hydantoins Employing Barium Hydroxide ...
Ho-Yeong Sohn (3044253), Young-Dae Gong (1463149), Mark J. Kurth (1328874)   +2 more
core   +1 more source