Results 91 to 100 of about 2,171 (198)
Antinociceptive Effect of Hydantoin 3-Phenyl-5-(4-ethylphenyl)-imidazolidine-2,4-dione in Mice
Molecules, 2015 Imidazolidine derivatives, or hydantoins, are synthetic compounds with different therapeutic applications. Many imidazolidine derivatives have psychopharmacological properties, such as phenytoin, famous for its anticonvulsant efficacy, but also effective
Ronaldo Bezerra de Queiroz +11 more
doaj +1 more source
Facile one-pot synthesis of 5-substituted hydantoins.
, 2008 5-Substituted and 5,5-disubstituted hydantoins are synthesised from the corresponding aldehydes or ketones, using a one-pot, gallium(III) triflate-catalysed procedure that is compatible with a range of substrates and ...
Le Strat, F +8 more
core +1 more source
Beilstein Journal of Organic Chemistry, 2015 The mechanism and selectivity of a bicyclic hydantoin formation by selenium-induced cyclization are investigated. The proposed mechanism involves the intermediates formed by an electrophilic addition of the selenium reagent on a double bond of the ...
Biljana M. Šmit +3 more
doaj +1 more source
Twisted N‑Acyl-hydantoins: Rotationally Inverted Urea-Imides of Relevance in N–C(O) Cross-coupling
, 2018 We report a combined structural and computational study on the properties of twisted acyclic hydantoins. These compounds feature cyclic urea-imide moiety that is widely found in bioactive compounds and is structurally related to the classic bridged ...
Roger Lalancette +7 more
core +2 more sources
Direct Cu-catalyzed N3-arylation of hydantoins
, 2019 A regioselective method for the N3-arylation of hydantoins is investigated. It constitutes an important development complementing classical cyclization strategies.
Peletis, Georgios
core
Palladium-catalysed asymmetric allylic alkylation of hydantoins using bench-stable chiral palladium precatalysts. [PDF]
Hydantoins are important heterocyclic scaffolds present in a number of pharmaceutically relevant compounds. We report here a practical, scalable and enantioselective Pd-catalyzed asymmetric allylic alkylation (Pd-AAA) approach to diversely substituted ...
Jean, A +9 more
core +1 more source
Hydantoins and thiohydantoins derived from 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
, 2006 The reaction of methyl (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate with isocyanates (phenyl, naphthalen-1-yl, cyclohexyl, (S)-1-methylbenzyl) in ether has been used to prepare N-substituted methyl (3S)-2-aminocarbonyl-1,2,3,4-tetrahydroisoquinoline ...
MACHACEK V. +3 more
core +1 more source
The Ugi Four-Component Reaction: Application in the synthesis of bis-hydantoins
Three new bis 1,3,5-trisubstituted hydantoins were synthesized by combining an Ugi four-component condensation reaction with a base induced cyclization.
Gülten, Şirin
core +1 more source
, 2016 Microwave-Mediated Intramolecular Carbanilide Cyclization to Hydantoins Employing Barium Hydroxide ...
Ho-Yeong Sohn (3044253) +2 more
core +1 more source