Results 31 to 40 of about 535,496 (303)
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
, 2019 Confined hydration and conformational flexibility are some of the challenges encountered for the rational design of selective antagonists of G-protein coupled receptors. We present a set of C3-substituted (-)-stepholidine derivatives as potent binders of
Cordone, Pierpaolo +7 more
core +2 more sources
Molecular Oncology, Volume 19, Issue 4, Page 1170-1187, April 2025.High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies +9 more
wiley +1 more source
Molecular Oncology, Volume 19, Issue 5, Page 1517-1531, May 2025.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source
FEBS Open Bio, Volume 15, Issue 4, Page 580-586, April 2025.Activation of amino acids by aminoacyl‐tRNA synthetases can be followed by a modified ATP/PPi exchange assay using radiolabelled γ‐[32P]ATP. The reaction is quenched at certain time points, followed by separation of the product ([32P]PPi) from the substrate (γ‐[32P]ATP) by thin‐layer chromatography (TLC).
Igor Živković +4 more
wiley +1 more source
Kinetic, Spectroscopic, and X-Ray Crystallographic Evidence for the Cooperative Mechanism of the Hydration of Nitriles Catalyzed by a Tetranuclear Ruthenium-μ-oxo-μ-hydroxo Complex [PDF]
, 2008 The tetranuclear ruthenium-oxo-hydroxo-hydride complex {[(PCy3)(CO)RuH]4(μ4-O)(μ3-OH)(μ2-OH)} (1) was found to be a highly cooperative catalyst for the nitrile hydration reaction. The cooperative mechanism of the hydration of benzonitrile was established
Lindeman, Sergey V. +2 more
core +1 more source
Comparing the rates of absorption and weight loss during a desorption test using near infrared spectroscopy [PDF]
, 2013 The importance of determining skin hydration has over the years prompt the development of many instruments and methods, specifically designed to assess this parameter or water contents especially in the stratum corneum, and have greatly matured to suit ...
Agache +16 more
core +1 more source