Results 111 to 120 of about 22,641 (251)

The synthesis and characterisation of some ortho-substituted phenoxyalkanoic acids and their derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society, 2006
The synthesis of 2-phenoxyalkanoic acids (ethanoic, propanoic, butanoic) was realised by the reaction of ortho-hydroxybenzamide respectively N-phenyl-o-hydroxybenzamide with a-halogenated acids in aqueous sodium hydroxide solution.
VALENTIN BADEA   +4 more
doaj  

Dipropargyl 2,2'-isophthaloylbis(hydrazinecarboxylate)

open access: yesMolbank, 2010
The synthesis of dipropargyl 2,2'-isophthaloylbis(hydrazinecarboxylate) (3) by an addition-elimination reaction between isophthalic dihydrazide (1) and dipropargyl dicarbonate (2) is reported.
Thimo Huber, David D. Díaz
doaj   +1 more source

2‐Pyrazoline‐5‐One Derivative Suppresses Cell Proliferation and Induces Apoptosis With Upregulation of Bax in Breast Cancer Cells

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
2‐Pyrazoline‐5‐one derivative inhibits proliferation and migration and induces Bax‐mediated apoptosis in breast cancer cells. ABSTRACT The most common cancer in women worldwide is still breast cancer. Among its subtypes, luminal A and triple‐negative breast cancers present significant therapeutic challenges due to intrinsic drug resistance and absence ...
Sevgi Kocyigit Sevinc   +3 more
wiley   +1 more source

Octanoic Hydrazide-Linked Chitooligosaccharides-2,5-Anhydro-d-Mannofuranose

open access: yes, 2016
Chitooligosaccharide with one 2,5-anhydro-d-mannofuranose unit at the reducing end (COSamf) was prepared by nitrous acid depolymerization of chitosan.
Stéphane Trombotto, Amani Moussa
core   +1 more source

Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 966-988, July 2026.
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo   +4 more
wiley   +1 more source

Synthesis of Phthaloylglycyl Hydrazide Derivatives: Selective Protection of Phthalimide Group from Hydrazinolysis

open access: yes, 2018
Background: N-phthalimide amino acid hydrazide is a class of compounds that have the potential therapeutic use. In general, hydrazinolysis of N-substituted amino acid(s) ester removes the ester group and yields the corresponding hydrazide.
Chander Mohan, Ankur Gera, Sandeep Arora
core   +1 more source

Self‐Immolative Gels: Programmable Degradation Using Self‐Immolative Linkers and Polymers

open access: yesChemistry – A European Journal, Volume 32, Issue 23, 16 June 2026.
Self‐immolative linkers and polymers undergo bond‐cleaving reaction cascades in response to specific stimuli. Their incorporation into gels can be harnessed to release cargo, induce property changes, or trigger degradation in a highly controlled manner. These functions can be employed in applications such as sensing and drug delivery.
Chuanfeng Li, Elizabeth R. Gillies
wiley   +1 more source

Synthesis and Antituberculosis Activity of New Hydrazide Derivatives

open access: yes, 2008
WOS: 000261440800007PubMed ID: 18720343The increasing clinical importance of drug-resistant mycobacterial pathogens, especially Mycobacterium tuberculosis, has lent additional urgency to microbiological research and new antimycobacterial compound ...
Zafer A. Kaplancikli   +7 more
core   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer   +6 more
wiley   +1 more source

Isonicotinic acid hydrazide - a reinvestigation

open access: yes, 1974
C6H7N30, orthorhombic, P212121, a = 14·915 (15), b=ll·400 (10), c=3.835 (5) Å, Dm= 1·417 (7), Dc= 1·395 g cm-3 and Z=4. The structure was refined by the least-squares method to an R of 0·072 for 699 observed reflexions.
Vijayan, M., Bhat, T. N., Singh, T. P.
core   +2 more sources

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