Histone deacetylase 8 (HDAC8) is a clinically validated target in neuroblastoma, where isoform selective inhibition offers a strategy to suppress tumour growth while limiting off‐target toxicity. Hydroxamic acids remain the dominant zinc‐binding group (ZBG) in HDAC inhibitors but are also associated with metabolic instability, suboptimal ...
Nathan Long +3 more
wiley +1 more source
A sustainable, ligand‐free Pd‐catalyzed borrowing hydrogen protocol in a biodegradable hydrophobic natural deep eutectic solvent (NADES) (thymol/DL‐menthol) enables the N‐alkylation of primary amines with benzylic alcohols under mild, aerobic conditions, allowing efficient reuse of both catalyst and solvent for seven consecutive cycles. The hydrophobic
Maryam Saeb +5 more
wiley +1 more source
Citation: 'hydrazide imides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02878 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Hypervalent Iodine‐Mediated Synthesis of Sulfones Using Organozinc Pivalates and Sulfinate Salts
A general protocol for sulfone synthesis via sulfonyl‐containing hypervalent iodine reagents and organozinc pivalates is described. The method is practical, provides a broad scope of sulfone in moderate to high yield. bicyclo[1.1.1]pentane‐sulfones are also disclosed and a one‐pot synthesis of Diels–Alder adduct is presented. Sulfones are key motifs in
José C. Cunha +4 more
wiley +1 more source
The influence of growth stage and application site on movement and effect of glyphosate in Cirsium arvense (L.) Scop. : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Plant Science at Massey University [PDF]
Glyphosate was applied at different rates to the upper parts of Cirsium arvense plants at various growth stages in a glasshouse experiment. Measurements and observations were made of the plants over a period of several months following treatment.
Harrington, Kerry Charles
core
Chemical weed control in strawberries. [PDF]
Includes bibliographical references (pages 32-33)
Hemphill, Delbert D., Roberts, W. W.
core
Amino Acids and Peptides. XIV, Synthesis of a Tetrapeptide Sequence (A5-A8) of Glucagon [PDF]
Author Institution: Department of Chemistry, Stanford University, Stanford, California 94305A synthesis of the tetrapeptide sequence A5-A8 of glucagon is described that employs various blocking groups, coupling procedures, and ...
Handford, Brian O. +2 more
core
Synthesis of N-(N’-benzoylhydrazinomethyl)benzamide
n ...
Emil Popovski
doaj +1 more source
Multifunctional pectin derivatives as anticancer agents in colorectal cancer via synthesis, computational insights, and modulation of NRF2/HO-1, HIF-1α, and VEGF/PDGF-D signaling pathways. [PDF]
Elsayed GH, Fahim AM.
europepmc +1 more source

