Results 61 to 70 of about 29,362 (316)

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

open access: yesAdvanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu   +4 more
wiley   +1 more source

Chemochromic Indicators for the Detection of Hypergolic Fuels [PDF]

open access: yes, 2010
The toxicity and hazard level associated with the use of hypergolic fuels necessitates the development of technology capable of detecting the presence of such fuels in a variety of different environments and conditions. The most commonly used sensors for
Captian, J.   +2 more
core   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

open access: yesAdvanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song   +11 more
wiley   +1 more source

EPR Study of Spin Labeled Brush Polymers in Organic Solvents [PDF]

open access: yes, 2011
Spin-labeled polylactide brush polymers were synthesized via ring-opening metathesis polymerization (ROMP), and nitroxide radicals were incorporated at three different locations of brush polymers: the end and the middle of the backbone, and the end of ...
Burts, Alan O.   +7 more
core   +2 more sources

Microenvironment‐Guided Evolution of ssDNA‐SWCNT Probes for Selective Recognition of Aggressive Prostate Cancer Phenotypes

open access: yesAdvanced Science, EarlyView.
Random ssDNA–SWCNT(single strand DNA‐single walled carbon nanotube) library is functionally screened and evolved using high‐throughput 3D prostate tumor spheroids via iterative positive and negative selection, enabling the identification of NIR‐II fluorescent ssDNA‐SWCNT nanoprobe specific for prostate cancer.
Dakyeon Lee   +8 more
wiley   +1 more source

1,3-Dipolar cycloadditions of azomethine imines [PDF]

open access: yes, 2015
Azomethine imines are considered 1,3-dipoles of the aza-allyl type which are transient intermediates and should be generated in situ but can also be stable and isolable compounds.
Nájera, Carmen   +2 more
core   +3 more sources

Light‐Promoted Hydrazine Dehydrogenation over Ni/NH2‐MIL‐125: Unraveling Mechanisms for Efficient Hydrogen Production

open access: yesAdvanced Science, EarlyView.
Highly dispersed and electron‐rich Ni nanoparticles (≈2.7 nm) supported on NH2‐MIL‐125 significantly promote the dehydrogenation of hydrous hydrazine under visible‐light irradiation, achieving a turnover frequency of 220.2 h−1 at 323 K, which is more than twice that in the dark (108.1 h−1) and outperforms most reported non‐precious metal catalysts ...
Jianjun Long   +6 more
wiley   +1 more source

Combinatorial Libraries on Rigid Scaffolds: Solid Phase Synthesis of Variably Substituted Pyrazoles and Isoxazoles

open access: yesMolecules, 1997
The synthesis of combinatorial compound libraries has become a powerful lead finding tool in modern drug discovery. The ability to synthesize rapidly, in high yield, new chemical entities with low molecular weight on a solid support has a recognized ...
Eduard R. Felder, Andreas L. Marzinzik
doaj   +1 more source

Synthesis and reactions of 1-amino-1,5,6,10b-tetrahydroimidazo[2,1-a]isoquinolin-2(3H)-ones [PDF]

open access: yes, 2008
1-Amino-1,5,6,10b-tetrahydroimidazo[2,1-a]isoquinolin-2(3H)-ones, as previously unknown ring-annelated isoquinolines with a 3-aminoimidazolidin-4-one scaffold, were selectively prepared upon reacting 2-carbamoylmethyl- or 2-ethoxycarbonylmethyl-3,4 ...
De Kimpe, Norbert   +5 more
core   +2 more sources

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