Results 71 to 80 of about 13,633 (275)

Combinatorial Libraries on Rigid Scaffolds: Solid Phase Synthesis of Variably Substituted Pyrazoles and Isoxazoles

open access: yesMolecules, 1997
The synthesis of combinatorial compound libraries has become a powerful lead finding tool in modern drug discovery. The ability to synthesize rapidly, in high yield, new chemical entities with low molecular weight on a solid support has a recognized ...
Eduard R. Felder, Andreas L. Marzinzik
doaj   +1 more source

Chemochromic Indicators for the Detection of Hypergolic Fuels [PDF]

open access: yes, 2010
The toxicity and hazard level associated with the use of hypergolic fuels necessitates the development of technology capable of detecting the presence of such fuels in a variety of different environments and conditions. The most commonly used sensors for
Captian, J.   +2 more
core   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Hydrazine monitoring in spacecraft [PDF]

open access: yes
Hydrazine (HZ) and monomethyl hydrazine (MMH) are highly toxic compounds used as fuels in the Space Shuttle Orbiter Main Engines and in its maneuvering and reaction control system.
Beck, S. W.   +3 more
core   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen   +10 more
wiley   +1 more source

Síntese e avaliação preliminar da atividade antinociceptiva de novas isoxazolil-aril-hidrazonas

open access: yesQuímica Nova, 2011
New 2-isoxazoline aldehydes were synthesized, in good yields, from cycloadduct of the 1,3-dipolar cycloaddition reaction between endocyclic enecarbamate and carboethoxyformonitrile oxide (CEFNO). Condensation of these 2-isoxazoline aldehydes with several
Sílvio Leandro Gonçalves Bomfim Reis   +8 more
doaj   +1 more source

4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis [PDF]

open access: yes, 2019
A new series of 4-(3-nitrophenyl)thiazol-2-ylhydrazone derivatives were designed, synthesised, and evaluated to assess their inhibitory effect on the human monoamine oxidase (hMAO) A and B isoforms. Different (un)substituted (hetero)aromatic substituents
Alcaro, Stefano   +10 more
core   +1 more source

Gas chromatographic column enables analysis of propellant hydrazines [PDF]

open access: yes, 1966
Stainless steel column is used in gas chromatographic analysis of propellant-grade hydrazine.
Welz, E. A., Jr.
core   +1 more source

Microwave-Assisted Synthesis of Some 3,5-Arylated 2-Pyrazolines

open access: yesMolecules, 2003
Condensation of 2-acetylnaphthalene with benzaldehydes under microwave irradiation affords chalcones which undergo facile and clean cyclizations with hydrazines RNHNH2 (R= H, Ph, Ac) to afford 3,5-arylated 2-pyrazolines in quantitative yields, also under
Hassan Ghasemnejad, Davood Azarifar
doaj   +1 more source

Extrusion - back to the future: using an established technique to reform automated chemical synthesis [PDF]

open access: yes, 2016
YesHerein, the benefits which extrusion can provide for the automated continuous synthesis of organic compounds are highlighted. Extrusion is a well-established technique that has a vital role in the manufacturing processes of polymers, pharmaceuticals ...
Crawford, Deborah E.
core   +2 more sources

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