Results 101 to 110 of about 59,471 (323)

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Molecular Cages as Probes in Indicator Displacement Assays: The Case of Scopolamine Detection

Angewandte Chemie, EarlyView.
In this research, we show the concept of molecular cages as probes in indicator displacement assays, focusing on scopolamine detection, a drug often used in drug‐facilitated sexual assaults. Drug sensing occurs via the drug‐induced transformation of non‐emissive [Fluorescein2⊂Cage] complex into [Scopolamine⊂Catenane] and highly emissive free ...
Giovanni Montà‐González, Eva Garrido, Estela Climent, Cristian Vicent, Ramón Martínez‐Máñez, Vicente Martí‐Centelles   +5 more
wiley   +2 more sources

Fe‐S Protein FDX1 Triggers Tumor‐Intrinsic Innate Immunity via Mitochondrial Nucleic Acids Release to Orchestrate Ferroptosis in CCRCC

Advanced Science, EarlyView.
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang, Shaoqing Yu, Wenjie Wei, Wen Tao, Tianwei Cai, Lequan Wen, Jiali Ye, Chi Zhang, Huayi Feng, Senming Cao, Baojun Wang, Xin Ma, Yan Huang, Xu Zhang   +13 more
wiley   +1 more source

Predictive, Data‐Driven Design of Red‐Light Photoredox Catalysts for C─Heteroatom Bond Formation

Angewandte Chemie, EarlyView.
From redox numbers to red light: Donor oxidation and core reduction potentials predict E0‐0 in cyanoarene dyes, guiding selection of an efficient red‐light catalyst, 4MeODPATPN (PC13). Under 620 nm light, PC13 facilitates Ni‐catalyzed C─heteroatom cross‐couplings (C─N, C─O, C─S) with high functional‐group tolerance and reduced hydrodehalogenation ...
Amir Gizatullin, Tingting Yuan, Sascha Grotjahn, Luigi Cavallo, Burkhard König, Chen Zhu, Magnus Rueping   +6 more
wiley   +2 more sources

Studies on Girard Hydrazones. II. Polarographic Reduction Mechanisms of Girard Hydrazones

Chemical and Pharmaceutical Bulletin, 1964
Polarographic reduction processes of Girard hydrazones of aliphatic and aromatic ketones were studied. From the results of controlled potential electrolysis, the two-electron reduction process proposed by Prelog and Hafliger for Girard-T Hydrazones of aliphatic and alicyclic ketones was found to be not correct, and a mechanism shown in scheme (4 ...
M, MASUI, H, OHMORI
openaire   +3 more sources

Synthesis and Characterization of Novel Hydrazone Derivatives of Isonicotinic Hydrazide and Their Evaluation for Antibacterial and Cytotoxic Potential [PDF]

, 2022
Muhammad Abdullah Shah, Ala Uddin, Muhammad Raza Shah, Imdad Ali, Riaz Ullah, Peer Abdul Hannan, Hidayat Hussain   +6 more
openalex   +1 more source

Microenvironment‐Guided Evolution of ssDNA‐SWCNT Probes for Selective Recognition of Aggressive Prostate Cancer Phenotypes

Advanced Science, EarlyView.
Random ssDNA–SWCNT(single strand DNA‐single walled carbon nanotube) library is functionally screened and evolved using high‐throughput 3D prostate tumor spheroids via iterative positive and negative selection, enabling the identification of NIR‐II fluorescent ssDNA‐SWCNT nanoprobe specific for prostate cancer.
Dakyeon Lee, Seok‐Hyeon Lee, Yunseo Jung, Jeongho Lee, Min‐Seo Choi, SaeOck Oh, Sungjee Kim, Byoung Soo Kim, Sanghwa Jeong   +8 more
wiley   +1 more source

Aggregation‐Induced Resonance Energy Transfer in Polymer Dots to Boost Electrochemiluminescence Performance for Bioimaging of Glycan on Cells

Advanced Science, EarlyView.
This study pioneers an aggregation‐induced resonance energy transfer mechanism by synergistically integrating aggregation‐induced emission (AIE), resonance energy transfer (RET), and thermally activated delayed fluorescence (TADF) within co‐reactant conjugated polymers to develop self‐enhanced ECL emitters, which achieves an ECL efficiency up to 92.6 ...
Chao Wang, Mengjiao Li, Yiran Li, Xiangfu Hu, Chunlan Li, Ningning Wang, Huangxian Ju   +6 more
wiley   +1 more source

The Effect of Pore Functionality in Multicomponent Covalent Organic Frameworks on Stable Long‐Term Photocatalytic H2 Production

Advanced Energy Materials, EarlyView.
Five COFs are synthesized through a multicomponent reaction, preserving a similar backbone while introducing varying pore functionalities. All COFs demonstrate excellent chemical stability and sustained H2 production under sunlight for 7‐15 days. The imidazole‐functionalized COF exhibits the highest H2 production, which can be attributed to its high ...
Prasenjit Das, Gouri Chakraborty, Jin Yang, Jérôme Roeser, Hüseyin Küçükkeçeci, Anh Dung Nguyen, Michael Schwarze, Jose Gabriel, Christopher Penschke, Shengjun Du, Vincent Weigelt, Islam E. Khalil, Johannes Schmidt, Peter Saalfrank, Martin Oschatz, Jabor Rabeah, Reinhard Schomäcker, Franziska Emmerling, Arne Thomas   +18 more
wiley   +1 more source

Selected reactive oxygen species and antioxidant enzymes in common bean after Pseudomonas syringae pv. phaseolicola and Botrytis cinerea infection [PDF]

, 2014
Phaseolus vulgaris cv. Korona plants were inoculated with the bacteria Pseudomonas syringae pv. phaseolicola (Psp), necrotrophic fungus Botrytis cinerea (Bc) or with both pathogens sequentially.
A Encina, A Imberty, A Koornneef, A Mika, A Polle, A Sakamoto, A Schouten, AC Maehly, Agata Nowogórska, AM Mayer, B Williamson, BA Adie, BPHJ Thomma, C Beauchamp, C Bowler, C Lamb, DG Mellersh, DJ Capaldi, F Garcia-Arenal, F Passardi, G Creissen, G Oudgenoeg, GJM Beckers, H Derksen, H Thordal-Christensen, HH Flor, I Finiti, J Glazebrook, J Patykowski, J Shi, Jacek Patykowski, JR Alfano, JS Thaler, K Laluk, KG Welinder, M Sedlářová, MC Mehdy, MC Romero-Puertas, MM Bradford, N Doke, N Shlezinger, P Baarlen Van, P Baptista, P Wojtaszek, PP Bolwell, R Goldberg, R Huckelhoven, R Schwacke, RS Dhindsa, S AbuQamar, S AbuQamar, S Dorey, S Takahashi, SJ Burr, T Mengiste, U Takahama, UK Laemmli   +56 more
core   +2 more sources