Results 111 to 120 of about 31,731 (271)

Converting Hydrazone-Based Photoswitches into Functional Materials

open access: yes, 2022
The development of new classes of molecular switches with enhanced performance and brand-new functionalities enables practitioners to push the frontiers of adaptive materials.
Yang, Sirun
core  

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá   +4 more
wiley   +1 more source

Hydrazone exchange in nanoparticle monolayers : a dynamic covalent approach for controlling nanomaterial properties

open access: yes, 2015
This Thesis reports the synthesis, purification and characterisation of gold nanoparticles (NPs) functionalised with a monolayer of hydrazone ligands in order to perform post-synthetic manipulations of the NP-bound monolayer exploiting dynamic ...
della Sala, Flavio
core  

Interface controlled current injection in hydrazone doped polyesters

open access: yes, 2010
The current injection properties of gold contacts fitted to hydrazone doped polyesters (HDPs) have been investigated using a series of thin-film Au/HDP/Al diode structures.
Goldie, D.M., D.M. Goldie
core   +1 more source

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

open access: yesSmall, EarlyView.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

Discotic Liquid Crystalline Hydrazone Compounds:  Synthesis and Mesomorphic Properties

open access: yes, 2016
1,3,5-Trisacetoacetamidobenzene with three 1,3-diketo groups was synthesized by the reaction of 1,3,5-triaminobenzene with diketene. Discotic hydrazone compounds were prepared by the diazo coupling reaction between 1,3,5-trisacetoacetamidobenzene and ...
Ji Young Chang (1719385)   +3 more
core   +1 more source

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

open access: yesThe Chemical Record, EarlyView.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source

Topical Anti-inflammatory evaluation of new hydrazone: 4-chloro-3-nitrobenzylidene) isonicotinohydrazide: Topical Anti-inflammatory evaluation

open access: yes, 2019
The anti-inflammatory effects of the investigated compounds; Isoniazid, hydrazone, and Indomethacin were evaluated in this study. The experiment was performed using xylene induced topical ear edema method in mice model, at the dose of (0.5 mg/ear ...
Madoui, Soraya   +6 more
core   +1 more source

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Advances in organic UV filters for sunscreens over the past decade

open access: yesPhotochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon   +4 more
wiley   +1 more source

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