Results 101 to 110 of about 10,821 (234)

Converting Hydrazone-Based Photoswitches into Functional Materials [PDF]

, 2022
The development of new classes of molecular switches with enhanced performance and brand-new functionalities enables practitioners to push the frontiers of adaptive materials.
Yang, Sirun
core  

Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents

Molecules, 2014
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl)furan-2-yl)methylene)hydrazinyl]-4-(4 ...
Mehlika Dilek Altıntop, Ahmet Özdemir, Gülhan Turan-Zitouni, Sinem Ilgın, Özlem Atlı, Fatih Demirci, Zafer Asım Kaplancıklı   +6 more
doaj   +1 more source

Chelating Picolinaldehyde Hydrazone Amides as Protecting Groups for Carboxylic Acids: Orthogonal Reactivities of Hydrazone Amides and Esters in Hydrolysis

We report a chelating hydrazone amide as a protecting group for carboxylic acids. Unlike most esters, 2-picolinaldehyde hydrazone amides are stable under acidic or basic hydrolytic conditions.
Yukiho Amano (14251468), Momoka Ando (14251474), Midori Hosoi (14251471), Mayuko Toyoda (14251465), Yasuhiro Nishikawa (1652077), Osamu Hara (1652068), Daiki Mori (3612515)   +6 more
core   +1 more source

Hydrogen-bonded dimers in 2-nitrobenzaldehyde hydrazone and a three-dimensional hydrogen-bonded framework in 3-nitrobenzaldehyde hydrazone

, 2004
Molecules of 2-nitrobenzaldehyde hydrazone, C7H7N3O2, where Z' = 2, are linked by two N-H...N hydrogen bonds into isolated dimers, whereas in the isomeric 3-nitrobenzaldehyde hydrazone, where Z' = 1, the molecules are linked by one N-H...O hydrogen bond ...
Low, JN, Skakle, JMS, Wardell, JL, Glidewell, Christopher   +3 more
core   +1 more source

Azine or hydrazone? The dilemma in amidinohydrazones

, 2015
Azines belong to an important class of compounds that are found to have numerous applications in medicinal chemistry. Hydrazones are related to azines and are more widely known compounds that carry many biochemical applications.
Chourasiya, Sumit S., Ramakrishnan, Ashok, Bharatam, Prasad V.   +2 more
core   +1 more source

Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit

Molecules, 2014
Nonsteroidal anti-inflammatory drugs (NSAIDs) 1–5 containing an N-acyl hydrazone subunit were prepared and their antiplatelet and antithrombotic activities assessed in vitro and in vivo.
Rafael Consolin Chelucci, Luiz Antônio Dutra, Maria Elisa Lopes Pires, Thais Regina Ferreira de Melo, Priscila Longhin Bosquesi, Man Chin Chung, Jean Leandro dos Santos   +6 more
doaj   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Synthesis, Identification and Preliminary Pharmacological Evaluation of New Hydrazone and 1, 3, 4-oxadiazole Derivatives of Ketorolac

Iraqi Journal of Pharmaceutical Sciences
New series of hydrazones (3a–b) and 1, 3, 4-oxadiazole S-alkylated derivatives (5a–b) of ketorolac (NSAID) were synthesized and their structures were identified by using ATR-FT-IR and ¹HNMR spectroscopic analytical techniques.
Aliaa AL-Hashemmi, Muthanna S. Farhan
doaj   +1 more source

Hydrazone Switch-Based Negative Feedback Loop

, 2016
A negative feedback loop that relies on the coordination-coupled deprotonation (CCD) of a hydrazone switch has been developed. Above a particular threshold of zinc­(II), CCD releases enough protons to the environment to trigger a cascade of reactions ...
Ivan Aprahamian (1336620), Susnata Pramanik (3345764)   +1 more
core   +1 more source

Hydrazide-Hydrazone derivatives and their antitubercular activity

This review aims to evaluate the mechanisms of action of current and emerging anti-TB drugs and molecules, emphasizing hydrazone functionality. Hydrazone compounds, featuring an azomethine group (R-1-HN-N=CR2R3), exhibit potent anti-TB and broad-spectrum
Thorat, B. R., Shah, Umang, de Oliveira, M. Santana, Lokesh, B. V. S., Agrawal, R., Shaik, A. B., Garg, A., Arvindekar, S. A., Mali, S. N., Cruz, J. N.   +9 more
core   +1 more source