Nitrofuran‐based hydrazones derived from furagin are developed as dual inhibitors of thioredoxin reductase 1 and cancer‐associated carbonic anhydrases IX and XII. The series shows selective enzyme inhibition with reduced off‐target carbonic anhydrase (CA) I/II activity, while lead compound 7g exhibits potent TrxR1 inhibition and moderate anticancer ...
Aleksandrs Pustenko +6 more
wiley +1 more source
Formaldehyde hydrazone as a methyl reagent for nickel-catalyzed cross-coupling methylation of aryl and heteroaryl electrophiles. [PDF]
Farajat D +10 more
europepmc +1 more source
Evaluation of the antimicrobial and NorA and MepA efflux pump inhibitory activity of a hydrazone derivative of hydralazine against Staphylococcus aureus. [PDF]
Belém KSTG +10 more
europepmc +1 more source
Sterisch überfrachtete Alken‐Photo‐Redox‐Schalter auf Basis von Chinolinium/Carben Bausteinen
Eine modulare Synthese einer neuen Klasse von Photo‐ und Redox‐Schaltern wird beschrieben, die auf der Kombination von Chinoliniumsalzen und Carbenen basiert. Das photochemische Schalten ermöglicht einen selektiven Wechsel zwischen gefalteten E/Z‐Isomeren, während das elektrochemische Schalten den Wechsel zwischen neutralen, radikalkationischen und ...
Chris Burdenski +10 more
wiley +1 more source
Metal-free Minisci C-H alkylation of hydrazones using aldehydes: an unexpected route to hydrazone-containing pyrimidine derivatives. [PDF]
Tirehdast A, Semeniuchenko V, Shiri A.
europepmc +1 more source
Overcrowded Alkene Photo‐Redox‐Switches Based on Quinolinium/Carbene Building Blocks
A modular synthesis of a new class of photo‐ and redox‐switches is described based on the combination of quinolinium salts and carbenes. Photochemical switching allows to selectively switch between folded E/Z isomers, while electrochemical switching allows to change between neutral, radical cation and dicationic oxidation states, which are all isolable
Chris Burdenski +10 more
wiley +1 more source
Experimental and DFT Investigation of a Vitamin B<sub>6</sub>-Derived Fluorescent Probe for Detection of Al<sup>3+</sup> and Ga<sup>3+</sup> Ions in a Buffered Aqueous DMSO Solution. [PDF]
Zavalishin MN, Guschin AA, Gamov GA.
europepmc +1 more source
Synthesis, characterization, <i>in vitro</i> and computational assessment of new xanthene hydrazone derivatives as promising vasorelaxant agents. [PDF]
El Mesky M +13 more
europepmc +1 more source
Advances in the Different Synthetic Routes of Fluorinated Hydrazines. [PDF]
Kyrko D, Crousse B.
europepmc +1 more source
Theoretical-experimental study of new synthesized hydrazine-hydrazone benzenesulfonamide inhibitors for carbon steel in a 1.0 M hcl: DFT, QSAR. [PDF]
Elgammal WE +5 more
europepmc +1 more source

