Results 121 to 130 of about 31,731 (271)

Pyridoxal isonicotinoyl hydrazone and analogues

open access: yes, 1989
The ultraviolet-visible absorption spectra of the orally effective iron chelator, pyridoxal isonicotinoyl hydrazone (PIH), and three analogues, pyridoxal benzoyl hydrazone (PBH), pyridoxal p-methoxybenzoyl hydrazone (P pMBH) and pyridoxal m-fluorobenzoyl
Vitolo, L.W.   +3 more
core  

Substrate‐specific mitochondrial dysfunction and metabolomic profiles in type 2 diabetic rat hearts

open access: yesExperimental Physiology, EarlyView.
Abstract Type 2 diabetes (T2D) greatly alters cardiac fuel handling, yet how mitochondrial function adapts to the diabetic substrate environment remains unclear. This study investigated substrate‐specific cardiac mitochondrial bioenergetics from a T2D rat model induced by a high‐fat diet and low‐dose streptozotocin.
Toan Pham
wiley   +1 more source

Hydrazone switches and things in between

open access: yes, 2017
This feature article surveys the various ways by which a structurally simple hydrazone can be used in accessing different functional materials, mainly photo/chemically activated switches, fluorophores and sensors.
Ivan Aprahamian
core   +1 more source

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga   +8 more
wiley   +1 more source

Spectroscopic Studies of some Benzilic Hydrazone Derivatives

open access: yes, 1997
Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt (Tanta University and Beni Suef Branch) Manuscript received 1 August 1995, revised 6 May 1996, accepted 2 September 1996 Spectroscopic Studies of some Benzilic Hydrazone ...
Y. M. ISSA   +3 more
core   +1 more source

hydrazide hydrazones

open access: yes, 2019
Citation: 'hydrazide hydrazones' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02877 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem   +3 more
wiley   +1 more source

APOE4 negates the effects of ovarian hormones on cerebrovascular endothelial and mitochondrial function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We examined the interaction effect of ovarian hormones and APOE genotype on cerebrovascular and mitochondrial function. Our data revealed that APOEε3 mice that were ovariectomized exhibited impaired endothelial function and greater oxidative stress and inflammation compared to sham controls.
Mackenzie N. Kehmeier   +9 more
wiley   +1 more source

Nucleophilic Catalysis of Hydrazone Formation and Transimination:  Implications for Dynamic Covalent Chemistry

open access: yes, 2016
Aniline accelerates hydrazone formation and transimination through nucleophilic catalysis. To demonstrate the method, unprotected peptides are reacted and then scrambled using a hydrazone reaction under conditions relevant for biological applications ...
Anouk Dirksen (1790116)   +3 more
core   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

open access: yesChirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz   +1 more
wiley   +1 more source

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