Results 121 to 130 of about 24,483 (218)

Furagin Derivatives—Nitrofuran‐Based Hydrazones as Potential Dual Inhibitors of Thioredoxin Reductase and Carbonic Anhydrases

open access: yesChemMedChem, Volume 21, Issue 13, 14 July 2026.
Nitrofuran‐based hydrazones derived from furagin are developed as dual inhibitors of thioredoxin reductase 1 and cancer‐associated carbonic anhydrases IX and XII. The series shows selective enzyme inhibition with reduced off‐target carbonic anhydrase (CA) I/II activity, while lead compound 7g exhibits potent TrxR1 inhibition and moderate anticancer ...
Aleksandrs Pustenko   +6 more
wiley   +1 more source

Formaldehyde hydrazone as a methyl reagent for nickel-catalyzed cross-coupling methylation of aryl and heteroaryl electrophiles. [PDF]

open access: yesNat Commun
Farajat D   +10 more
europepmc   +1 more source

Evaluation of the antimicrobial and NorA and MepA efflux pump inhibitory activity of a hydrazone derivative of hydralazine against Staphylococcus aureus. [PDF]

open access: yesArch Microbiol
Belém KSTG   +10 more
europepmc   +1 more source

Sterisch überfrachtete Alken‐Photo‐Redox‐Schalter auf Basis von Chinolinium/Carben Bausteinen

open access: yesAngewandte Chemie, Volume 138, Issue 29, 13 July 2026.
Eine modulare Synthese einer neuen Klasse von Photo‐ und Redox‐Schaltern wird beschrieben, die auf der Kombination von Chinoliniumsalzen und Carbenen basiert. Das photochemische Schalten ermöglicht einen selektiven Wechsel zwischen gefalteten E/Z‐Isomeren, während das elektrochemische Schalten den Wechsel zwischen neutralen, radikalkationischen und ...
Chris Burdenski   +10 more
wiley   +1 more source

Overcrowded Alkene Photo‐Redox‐Switches Based on Quinolinium/Carbene Building Blocks

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 29, 13 July 2026.
A modular synthesis of a new class of photo‐ and redox‐switches is described based on the combination of quinolinium salts and carbenes. Photochemical switching allows to selectively switch between folded E/Z isomers, while electrochemical switching allows to change between neutral, radical cation and dicationic oxidation states, which are all isolable
Chris Burdenski   +10 more
wiley   +1 more source

Synthesis, characterization, <i>in vitro</i> and computational assessment of new xanthene hydrazone derivatives as promising vasorelaxant agents. [PDF]

open access: yesRSC Adv
El Mesky M   +13 more
europepmc   +1 more source

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