Results 121 to 130 of about 10,821 (234)
Journal of Applied Toxicology, EarlyView.ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü +3 more
wiley +1 more source
, 2019 The anti-inflammatory effects of the investigated compounds; Isoniazid, hydrazone, and Indomethacin were evaluated in this study. The experiment was performed using xylene induced topical ear edema method in mice model, at the dose of (0.5 mg/ear ...
Madoui, Soraya +6 more
core +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT A Cu(II) complex derived from a pyrimidine with the isatin group was synthesized and tested for its cytotoxic effects on A549 lung cancer and MCF‐7 breast cancer cell lines, as well as its effects on apoptosis‐associated cell death and cell cycle regulation in A549 cells. To evaluate cytotoxicity, MTT assays were performed at 24, 48, and 72 h,
Müjgan Kesik Oktay +4 more
wiley +1 more source
, 2019 Citation: 'hydrazide hydrazones' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02877 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Interface controlled current injection in hydrazone doped polyesters
, 2010 The current injection properties of gold contacts fitted to hydrazone doped polyesters (HDPs) have been investigated using a series of thin-film Au/HDP/Al diode structures.
Goldie, D.M., D.M. Goldie
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Coupled Environmental Effects in Competitive Inhibition of Dynamic Hydrazone Hydrogels
Macromolecular Rapid Communications, EarlyView.Environment Alters Competitive Inhibition of Crosslinks. Ion concentration, pH, and buffer composition govern exchange kinetics and network stability in dynamic benzyl‐hydrazone hydrogels. These factors are particularly important when utilizing small‐molecule competitors for enhanced control over gel mechanics, underscoring the need to control the ...
Sirilak Mekcham +5 more
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
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Recent Advances in Hydrazone as Organometallic Equivalent—HOME Chemistry
To enable sustainable carbon–carbon (C–C) bond construction in organic synthesis, our group has developed a novel strategy termed HOME chemistry—hydrazone as organometallic equivalent.
Wei Zhang +3 more
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Senotherapeutics for Knee Osteoarthritis
Medicinal Research Reviews, EarlyView.ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source
Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies
Medicinal Research Reviews, EarlyView.ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva +23 more
wiley +1 more source