Results 161 to 170 of about 31,731 (271)

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

open access: yesJournal of Applied Toxicology, Volume 46, Issue 6, Page 1987-2002, June 2026.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu   +6 more
wiley   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu   +9 more
wiley   +1 more source

Culture Optimization of the IPEC–J2 Piglet Jejunum Cell Line for Applications in Infant Nutrition Research

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 12, 28 June 2026.
IPEC–J2 cell line is derived from piglet jejunal cells. Four different culture media were assessed for their ability to support IPEC‐J2 differentiation into an in vitro gut barrier. PS10 media proved most successful. Once differentiated with PS10, the IPEC‐J2 barrier was sufficiently robust for treatment with digested infant food. This demonstrates the
Francesca Bietto   +6 more
wiley   +1 more source

Ultrasound‐Assisted Synthesis and Comprehensive Characterization of Nanosized VO(II), Fe(III), and Ru(III) Complexes: From Density Functional Theory/Nonlinear Optical Properties to Pharmaceutical Applications and Docking Insights

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Ultrasound‐assisted synthesis enabled the formation of ultrafine hydrazone‐based metal complexes with controlled nanostructures and enhanced stability. Density functional theory revealed optimized geometries and electronic properties. The nanosized complexes exhibited superior antimicrobial, anticancer, and antioxidant activities, supported by ...
R. A. El‐Kasaby   +7 more
wiley   +1 more source

Synthesis, characterization, <i>in vitro</i> and computational assessment of new xanthene hydrazone derivatives as promising vasorelaxant agents. [PDF]

open access: yesRSC Adv
El Mesky M   +13 more
europepmc   +1 more source

The Dithiirane–Thiosulfine Equilibrium Revisited—A Computational Study of Structure, Thermodynamics and Kinetics

open access: yesJournal of Physical Organic Chemistry, Volume 39, Issue 6, June 2026.
The dithiirane–thiosulfine equilibrium has been revisited by means of modern computational chemistry tools to shed light on whether stable thiosulfines might be isolated. ABSTRACT Thiosulfines as reactive S‐centered 1,3‐dipoles undergoing (3 + 2)‐cycloadditions are still of interest in the chemistry of sulfur‐rich heterocycles.
Dirk Buddensiek, Thomas Behrens
wiley   +1 more source

Recent Advances in Photoelectrochemical Water Splitting Enabled by Covalent Organic Frameworks

open access: yesSmall Structures, Volume 7, Issue 6, June 2026.
This review highlights the potential of 2D covalent organic frameworks (COFs) as tunable and porous photoactive catalysts for solar‐driven water splitting. It discusses COF design principles and emerging photoelectrocatalytic performance, with special emphasis on film fabrication and deposition strategies critical for integrating COFs into efficient ...
Roman Guntermann   +3 more
wiley   +1 more source

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