Computer assisted synthesis and in-vitro cytotoxic evaluation of new pyrazole-fused isoquinolinoquinones derivatives as PI3K receptor antagonist with promising antitumoral activity [PDF]
, 2016 The importance of pyrazole and isoquinoline-5,8-dione scaffolds in medical chemistry is underlined by the high number of drugs currently on trading that contains these active ingredients.
Crotti, Simone
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A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation [PDF]
, 2019 Brain tumor, as any type of cancer, is assumed to be sustained by a small subpopulation of stem-like cells with distinctive properties that allow them to survive conventional therapies and drive tumor recurrence. Thus, the identification of new molecules
Cecília M. P. Rodrigues +4 more
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A convenient synthesis of 5-amino-4-(2-benzothiazolyl)pyrazoles [PDF]
, 1997 1175 ...
Abdallah, Magda A +3 more
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Synthesis and functionalization of a lactam-pyrazole molecular scaffold as a promising anticancer compound [PDF]
, 2015 The importance of pyrazole and lactam-based molecules in medical and pharmaceutical fields is underlined by the multitude of active ingredients on trade, such as Sildenafil or Apixaban, by Pfizer.
Bertuzzi, Giulio
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[3+2]-Cycloaddition of Nitrile Imines to Parabanic Acid Derivatives-An Approach to Novel Spiroimidazolidinediones. [PDF]
Int J Mol Sci, 2023 Kuznetsova JV +12 more
europepmc +1 more source
Aspects of the chemistry of some highly crowded aromatic ligands [PDF]
, 1990 A series of ortho-substituted arylchlorophosphoranes has been prepared. The structures of these compounds have been studied by the use of (^31)Cl n.q.r. and solid-state (^31)P n.m.r. . It has been shown that ortho substitution by groups such as CH(_3) or
Straw, T. A.
core
Contribution of Halides in CsX (X=Cl, Br and I) Thin Films on the formation of SPR peaks [PDF]
arXiv, 2013 This manuscript describes the evolution of grain structures in Cesium Halide films which results in appearance of Surface Plasmon Resonance (SPR) peaks in UV-visible absorption spectra. Thin films of Cesium Halide grown by thermal evaporation are polycrystalline in nature with large irregular tightly packed grains with sharp grain boundaries. With time
arxiv
Synthesis and antimicrobial activity of new series of thiazoles, pyridines and pyrazoles based on coumarin moiety. [PDF]
Sci Rep, 2023 Sayed MT, Elsharabasy SA, Abdel-Aziem A.
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