Results 91 to 100 of about 39,725 (197)

Trifluoromethylated hydrazones and acylhydrazones as potent nitrogen-containing fluorinated building blocks. [PDF]

Beilstein J Org Chem, 2023
Dongxu Z.
europepmc   +1 more source

Synthesis and reactions of indane‐1,3‐dione‐2‐thiocarboxanilides with hydrazonoyl halides and active chloromethylene compounds

Heteroatom Chemistry, 2002
AbstractA novel synthesis of thiadiazoline derivatives 12 and 14 via treatment of indane‐1,3‐dione‐2‐thiocarboxanilides (5) with hydrazonoyl halides 1 and 2 is reported. Also, active chloromethylene compounds 15 react with 5 to give thiazole derivatives 19. © 2002 Wiley Periodicals, Inc.
Nehal M. Elwan, Huwaida M. Hassaneen, Hamdi M. Hassaneen   +2 more
openaire   +1 more source

Novel thiazolyl-pyrimidine derivatives as potential anticancer agents: Synthesis, biological evaluation, and molecular docking studies

Results in Chemistry
We synthesized and spectroscopically confirmed a series of 1,3-thiazolyl-pyrimidine derivatives to investigate their potential role in cancer therapy.
Tariq Z. Abolibda, Abdel-Aziz A.A. El-Sayed, Basant Farag, Magdi E.A. Zaki, Abdulwahed Alrehaily, Hossein M. Elbadawy, Ahmad A. Al-Shahri, Saleh R. Alsenani, Sobhi M. Gomha   +8 more
doaj   +1 more source

Synthesis of Aminocarbonyl N‑Acylhydrazones by a Three-Component Reaction of Isocyanides, Hydrazonoyl Chlorides, and Carboxylic Acids

, 2016
A novel one-pot multicomponent synthesis of α-aminocarbonyl N-acylhydrazones starting from readily available hydrazonoyl chlorides, isocyanides, and carboxylic acids is reported.
Fiorella Meneghetti (1493926), Mariateresa Giustiniano (1520011), Ettore Novellino (333902), Gian Cesare Tron (1520005), Valentina Mercalli (1520014), Francesco Giustiniano (1734631), Monica Varese (1520002)   +6 more
core   +1 more source

Synthesis of aminocarbonyl N-acylhydrazones by a three-component reaction of isocyanides, hydrazonoyl chlorides, and carboxylic acids

, 2014
A novel one-pot multicomponent synthesis of α-aminocarbonyl N-acylhydrazones starting from readily available hydrazonoyl chlorides, isocyanides, and carboxylic acids is reported.
GIUSTINIANO, MARIATERESA, E. Novellino, G. C. Tron, F. Meneghetti, F. Giustiniano, Meneghetti, Fiorella, Giustiniano, Francesco, NOVELLINO, ETTORE, M. Varese, Mercalli, Valentina, Varese, Monica, V. Mercalli, Tron, Gian Cesare, M. Giustiniano   +13 more
core   +1 more source

Novel imidazoles from guanylhydrazone: Synthesis, computational, and molecular docking studies as α-amylase inhibitors for type 2 diabetes management

Results in Chemistry
This study reports a facile synthesis of novel imidazole derivatives as potential α-amylase inhibitors for type 2 diabetes management. Starting with readily available precursors (p-chloroacetophenone and aminoguanidine), guanylhydrazone 3 was synthesized
Mohamed G. Badrey, Ahmed A. Elhenawy, Mohammad Mahboob Alam, Syed Nazreen, Magdi E.A. Zaki, Sobhi M. Gomha   +5 more
doaj   +1 more source

Synthesis, characterization, and in silico studies of substituted 2,3-dihydro-1,3,4-thiadiazole derivatives

Results in Chemistry
The reaction of hydrazonoyl halides with different carbodithioate derivatives in the presence of triethylamine was studied, resulting in the synthesis of a series of unsymmetrical azine derivatives with yields ranging from 64 % to 80 %. The structures of
Yasser H. Zaki, Sobhi M. Gomha, Basant Farag, Magdi E.A. Zaki, Ahmed M. Hussein   +4 more
doaj   +1 more source

One-flask synthesis of 1,3,5-trisubstituted 1,2,4- triazoles from nitriles and hydrazonoyl chlorides via 1,3-dipolar cycloaddition

, 2014
[[abstract]]A new “one-flask” synthesis of 3,5-disubstituted 1,2,4-triazoles has successfully been developed to synthesize a series of 3,5-disubstituted 1,2,4-triazoles.
Wang, Li-Ya;Wang, Li-Ya;蔡建鈞;Tsai, Henry J;Lin, Hui-Yi;Lin, Hui-Yi;Ka, Kimiyoshi;Kaneko, Kimiyoshi;Che, Fen-Ying;Cheng, Fen-Ying;Sh, Hsin-Siao;Shih, Hsin-Siao;Won, Fung Fuh;Wong, Fung Fuh;Hu, Jiann-Jyh;Huang, Jiann-Jyh
core  

Cyanauric Chloride as a key precursor and a core component for Three-Armed Triazolopyrimidines: Recent finding about SARs and docking analyses

Results in Chemistry
The s-triazine trichloride is a reactive compound and can be used as key intermediate for delivering polysubstituted triazines specially the three-armed ones.
Mohamed G. Badrey, Sobhi M. Gomha, Magdi E.A. Zaki, Basant Farag, Ahmed A.M. El-Reedy   +4 more
doaj   +1 more source

One-Pot Synthesis of Novel Thiazoles as Potential Anti-Cancer Agents

Drug Design, Development and Therapy, 2020
Abdelwahed R Sayed,1,2 Sobhi M Gomha,3,4 Eman A Taher,5,6 Zeinab A Muhammad,5 Hesham R El-Seedi,6,7 Hatem M Gaber,5 Mahgoub M Ahmed8 1Department of Chemistry, Faculty of Science, KFU, Hofuf, Saudi Arabia; 2Department of Chemistry, Faculty of Science ...
Sayed AR, Gomha SM, Taher EA, Muhammad ZA, El-Seedi HR, Gaber HM, Ahmed MM   +6 more
doaj