Results 91 to 100 of about 586 (203)

Synthesis of Some New Substituted Imidazo (1, 2-a) Pyridines and Their 2-One Derivatives [PDF]

, 2016
2, 3-diaminopyridine (11)(a tri-nitrogen nucleophile) undergoes regioselective cyclocondensation reaction with nitrilimines (2, 10) affording 8-aminoimidazo [1, 2-a] pyridines (12) and 8-aminoimidazo [1, 2-a] pyridine-2-ones (13), respectively.
Abu Thaher, Bassam A.
core  

Exocyclic enaminones as building blocks for synthesis of bioactive polyheterocyclic compounds [PDF]

, 2014
The reaction of exocyclic enaminones namely, 2-(dimethylaminomethylene)-3,4-dihydro-2H-naphthalen-1-one,  3-(dimethylaminomethylene)-thiochroman-4-one and 2-(dimethyl-aminomethylene)-indane-1,3-dione, each with heterocyclic diazonium salts afforded the ...
Abdallah, Magda A., Aziza, Mohamed R. Abdel, Farghaly, Thoraya A.   +2 more
core   +1 more source

Hydrazonoyl Halides as Precursors for Synthesis of Novel Bioactive Thiazole and Formazan Derivatives

Journal of Chemical Research, 2012
A new series of substituted 4-methyl-5-(arylazo)-2-[ N‘-(6,7,8,9-tetrahydro-benzocyclohepten-5-ylidene)-hydrazino]-thiazoles and 5-(arylhydrazono)-2-[ N‘-(6,7,8,9-tetrahydro-benzocyclohepten-5-ylidene)-hydrazino]-thiazol-4-one were prepared by reaction of hydrazonoyl chlorides with a thiosemicarbazone derivative.
Thoraya A. Farghaly, Eman M.H. Abbas
openaire   +1 more source

Design and synthesis of novel hybrids incorporating thiadiazole or thiazole-naphthalene: Anticancer assessment and molecular docking study

Results in Chemistry
To underscore the significance of thiazole and thiadiazole moieties in advancing cancer treatment and support researchers in drug design, we developed a novel series of 1,3,4-thiadiazole and 1,3-thiazole derivatives. These were synthesized by reacting 2-(
Jehan Y. Al-Humaidi, Lamia A. Albedair, Basant Farag, Magdi E.A. Zaki, Yousef E. Mukhrish, Sobhi M. Gomha   +5 more
doaj   +1 more source

Computer assisted synthesis and in-vitro cytotoxic evaluation of new pyrazole-fused isoquinolinoquinones derivatives as PI3K receptor antagonist with promising antitumoral activity [PDF]

, 2016
The importance of pyrazole and isoquinoline-5,8-dione scaffolds in medical chemistry is underlined by the high number of drugs currently on trading that contains these active ingredients.
Crotti, Simone
core  

1,3,4‐Thia‐ and‐ Selenadiazole and 1,2,4‐Triazolo[4,3‐a]pyrimidine Derivatives from Hydrazonoyl Halides.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Nadia A. Abdel‐Riheem, Nora M. Rateb, Ali A. Al‐Atoom, Abdou O. Abdelhamid   +3 more
openaire   +1 more source

Trifluoromethylated hydrazones and acylhydrazones as potent nitrogen-containing fluorinated building blocks. [PDF]

Beilstein J Org Chem, 2023
Dongxu Z.
europepmc   +1 more source

Novel thiazolyl-pyrimidine derivatives as potential anticancer agents: Synthesis, biological evaluation, and molecular docking studies

Results in Chemistry
We synthesized and spectroscopically confirmed a series of 1,3-thiazolyl-pyrimidine derivatives to investigate their potential role in cancer therapy.
Tariq Z. Abolibda, Abdel-Aziz A.A. El-Sayed, Basant Farag, Magdi E.A. Zaki, Abdulwahed Alrehaily, Hossein M. Elbadawy, Ahmad A. Al-Shahri, Saleh R. Alsenani, Sobhi M. Gomha   +8 more
doaj   +1 more source

Aspects of the chemistry of some highly crowded aromatic ligands [PDF]

, 1990
A series of ortho-substituted arylchlorophosphoranes has been prepared. The structures of these compounds have been studied by the use of (^31)Cl n.q.r. and solid-state (^31)P n.m.r. . It has been shown that ortho substitution by groups such as CH(_3) or
Straw, T. A.
core  

Novel imidazoles from guanylhydrazone: Synthesis, computational, and molecular docking studies as α-amylase inhibitors for type 2 diabetes management

Results in Chemistry
This study reports a facile synthesis of novel imidazole derivatives as potential α-amylase inhibitors for type 2 diabetes management. Starting with readily available precursors (p-chloroacetophenone and aminoguanidine), guanylhydrazone 3 was synthesized
Mohamed G. Badrey, Ahmed A. Elhenawy, Mohammad Mahboob Alam, Syed Nazreen, Magdi E.A. Zaki, Sobhi M. Gomha   +5 more
doaj   +1 more source