Results 71 to 80 of about 39,725 (197)

Recent Applications of Sulfonium Salts in Synthesis and Catalysis

open access: yesChemistry – A European Journal, Volume 30, Issue 70, December 13, 2024.
This review summarizes the recent developments on the synthetic applications of sulfonium salts with an emphasis on the description of the operating mechanistic pathways. Abstract The use of sulfonium salts in organic synthesis has experienced a dramatic increase during the last years that can arguably be attributed to three main factors; the ...
Sven Timmann, Zeyu Feng, Manuel Alcarazo
wiley   +1 more source

When Hydrazonoyl Chlorides Meet Terminal Alkynes: Regioselective Copper(I)-Catalysed "Click" Sequential Reactions to 5-Substituted Pyrazoles [PDF]

open access: yes, 2020
n the presence of catalytic amounts of copper(I) salts, terminal alkynes underwent the formation of copper(I) acetylides that enabled their nucleophilic addition onto hydrazonoyl chlorides followed by spontaneous cyclisation of the resulting ...
Molteni, Giorgio
core   +1 more source

Synthesis, Antitumor Evaluation and Molecular Docking of New Morpholine Based Heterocycles

open access: yesMolecules, 2017
A series of new morpholinylchalcones was prepared and then used as building blocks for constructing a series of 7-morpholino-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones via their reaction with 6-aminothiouracil.
Zeinab A. Muhammad   +5 more
doaj   +1 more source

Controlling (E/Z)‐Stereoselectivity of −NHC=O Chlorination: Mechanism Principles for Wide Scope Applications

open access: yesChemistry – A European Journal, Volume 30, Issue 60, October 28, 2024.
Due to the increasing interest in halo compounds in chemotherapy and protein modification/targeting in chiral bioenvironments, controlling the halogenation stereoselectivity is state‐of‐the‐art science. Halogenation of carbamoyl group (−NHC=O) has never been mechanistically studied. Herein, we dive into depths of regioselectivity and stereoselectivity,
Raed M. Maklad   +3 more
wiley   +1 more source

Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study

open access: yesDrug Design, Development and Therapy, 2021
Sobhi M Gomha,1,2 Hyam A Abdelhady,2 Doaa ZH Hassain,2 Aboubakr H Abdelmonsef,3 Mohamed El-Naggar,4 Mahmoud M Elaasser,5 Huda K Mahmoud2 1Chemistry Department, Faculty of Science, Islamic University in Almadinah Almonawara, Almadinah Almonawara, 42351 ...
Gomha SM   +6 more
doaj  

Design, Efficient Synthesis, Mechanism of Reaction and Antiproliferative Activity Against Cancer And Normal Cell Lines of A Novel Class of Fused Pyrimidine Derivatives [PDF]

open access: yes, 2018
This work concentrated on the utility of hydrazonoyl halides in synthesis of bioactive heterocycles like triazoles, pyrazoles, pyrimidines and their fused derivatives which have a wide spectrum of pharmaceutical value.
roaiah, hanaa F.   +5 more
core  

Synthesis and Biological Evaluation of Some Novel Thiazole-Based Heterocycles as Potential Anticancer and Antimicrobial Agents

open access: yesMolecules, 2019
A novel series of thiazole-based heterocycles was synthesized using 1,3-dipolar cycloaddition reactions in the presence of chitosan-grafted-poly(vinylpyridine) as an eco-friendly biopolymeric basic catalyst.
Sraa Abu-Melha   +5 more
doaj   +1 more source

A Convenient Ultrasound-Promoted Synthesis of Some New Thiazole Derivatives Bearing a Coumarin Nucleus and Their Cytotoxic Activity

open access: yesMolecules, 2012
Successful implementation of ultrasound irradiation for the rapid synthesis of a novel series of 3-[1-(4-substituted-5-(aryldiazenyl)thiazol-2-yl)hydrazono)ethyl]-2<em>H</em>-chromen-2-ones<strong> 5a</strong>–<strong>h< ...
Sobhi M. Gomha, Khaled D. Khalil
doaj   +1 more source

The temperature dependence of the F band in magnesium oxide [PDF]

open access: yes, 1968
The position and width of the F band in magnesium oxide have been measured in the temperature range 4-400 °K. The data have been analysed in terms of the simplest adequate `configuration coordinate' model. The width results give an effective frequency of
HENDERSON, B, STONEHAM, AM, KING, RD
core  

Bis-Hydrazonoyl chloride as precursors for synthesis of novel polysubstituted bis-azoles [PDF]

open access: yes, 2013
A series of novel bis-pyrazole, bis(imidazo[1,2-b][1,2,4]triazole) and bis(imidazo[1,2-a]benzimidazole) derivatives were synthesized via bis-hydrazonoyl chloride.
Farghaly, Thoraya Abdel Reheem   +1 more
core   +1 more source

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