Results 51 to 60 of about 39,725 (197)

Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are now increasingly recognized as highly adaptable platforms for synthetic design.
A. Lanfranco, M. Rusconi, J. Saglietto, P. Renzi, A. Deagostino, E. Azzi   +5 more
wiley   +1 more source

Synthesis and Reactivity of 2-(6,7-Diethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile towards Hydrazonoyl Halides

, 2001
The synthesis of 2-(6,7-diethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile (1) has been performed by ring closure of the corresponding amide according to the Bischler-Napieralski method (Scheme 1).
Heimgartner, Heinz, Linden, Anthony; https://orcid.org/, Hassaneen, Hamdi M, Awad, Enas M, Elwan, Nehal M   +4 more
core   +1 more source

3-Amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3H-chromeno [2,3-d ]pyrimidine: An Effecient Key Precursor for Novel Synthesis of Some Interesting Triazines and Triazepines as Potential Anti-Tumor Agents

Molecules, 2012
A number of interesting heterocycles were prepared through interaction of the intermediate 3-amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3H-chromeno-[2,3-d]pyrimidine (1) and reagents such as hydrazonyl halides 2 to furnish triazine derivatives
Sobhi M. Gomha, Mohamed G. Badrey
doaj   +1 more source

Synthesis, Characterization, and DFT of Some Thiazole Derivatives as Carbon Steel Corrosion Inhibitors in 1 M HCl

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
By reacting 2‐(1‐(4‐aminophenyl)ethylidene)hydrazine‐1‐carbothioamide (1) with various α‐halocarbonyl compounds, such as 3‐chloropentane‐2,4‐dione 2 and 1‐chloro‐1‐((4‐substituted phenyl)diazenyl)propan‐2‐one 4a–c, this work produces a new series of thiazole derivatives 3 and 5a–c.
Ahmed O. Mahmoud, Ghada Y. Elewady, Ahmed E. Suliman, Abdelfattah M. Ouf, Ghada E. Abdel‐Ghani   +4 more
wiley   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Reaction of Nitrilimines with Pyruvaldehyde Hydrazones: Synthesis and Antimicrobial Evaluation of Some New 1,2,4‐Triazole Derivatives

Journal of Chemistry, Volume 2015, Issue 1, 2015., 2015
A new series of 1,3,4,5,5‐pentasubstituted‐1,2,4‐triazoles (4a–j, 6a–j) have been synthesized by the 1,3‐dipolar cycloaddition of suitable nitrilimines 2 to pyruvaldehyde (2‐oxopropanal) hydrazones having (COPh, COOMe, COOEt, Me/Me, and Me/Ph) groups 3 and 5.
Hany M. Dalloul, Sevgi Kolaylı
wiley   +1 more source

Eco-Friendly Synthesis, Characterization and Biological Evaluation of Some Novel Pyrazolines Containing Thiazole Moiety as Potential Anticancer and Antimicrobial Agents

Molecules, 2018
The one-pot synthesis of a series of pyrazoline derivatives containing the bioactive thiazole ring has been performed through a 1,3-dipolar cycloaddition reaction of N-thiocarbamoylpyrazoline and different hydrazonoyl halides or α-haloketones in the
Mastoura M. Edrees, Sraa Abu- Melha, Amirah M. Saad, Nabila A. Kheder, Sobhi M. Gomha, Zeinab A. Muhammad   +5 more
doaj   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Synthesis and Antibacterial Activity of New Spiro[thiadiazoline‐(pyrazolo[3,4‐d]pyrimidine)] Derivatives

Journal of Chemistry, Volume 2015, Issue 1, 2015., 2015
New heterocyclic compounds spiroderivatives of allopurinol of biological interest were prepared from allopurinol via thionation and 1,3‐dipolar cycloaddition and were produced in high to excellent yields. These compounds were characterized on the basis of spectral and spectroscopic data (1H NMR, 13C, IR, and MS).
Mohammed El Fal, Youssef Ramli, Abdelfettah Zerzouf, Ahmed Talbaoui, Youssef Bakri, El Mokhtar Essassi, Marco Radi   +6 more
wiley   +1 more source

Utility of N-aryl 2-aroylhydrazono-propanehydrazonoyl chlorides as precursors for synthesis of new functionalized 1,3,4-thiadiazoles with potential antimicrobial activity

Journal of Advanced Research, 2015
Starting from N-aryl 2-aroylhydrazono-propanehydrazonoyl chlorides, a series of new functionalized 1,3,4-thiadiazoles were prepared. The structures of the compounds prepared were confirmed by both elemental and spectral analyses as well as by alternate ...
Abdou O. Abdelhamid, Sobhi M. Gomha, Ahmad S. Shawali   +2 more
doaj   +1 more source