Results 41 to 50 of about 586 (203)

Synthesis of novel thiazole, pyranothiazole, thiazolo[4,5-b]pyridines and thiazolo[5′,4′:5,6]pyrano[2,3-d]pyrimidine derivatives and incorporating isoindoline-1,3-dione group

BMC Chemistry, 2019
Background Thiazole is a core structural motif presents in a wide range of natural products. Thiazole derivatives also have a wide range of medicinal and biological properties. Results The reaction of hydrazonoyl halides with 2-(1-(4-(1,3-dioxoisoindolin-
Mona A. Hosny, Yasser H. Zaki, Wafaa A. Mokbel, Abdou O. Abdelhamid   +3 more
doaj   +1 more source

Novel thiadiazole-thiazole hybrids: synthesis, molecular docking, and cytotoxicity evaluation against liver cancer cell lines

Journal of Taibah University for Science, 2022
One of the worst diseases, cancer claims millions of lives each year throughout the world, necessitating the creation of novel treatments. In this study, we designed a novel series of 1,3,4-thiadiazoles through the reaction of 2-(4-methyl-2-(2-(1 ...
Ghadah F. Aljohani, Tariq Z. Abolibda, Mohammad Alhilal, Jehan Y. Al-Humaidi, Suzan Alhilal, Hoda A. Ahmed, Sobhi M. Gomha   +6 more
doaj   +1 more source

Silver(I) Salts as Useful Reagents in Pyrazole Synthesis [PDF]

, 2007
n/
GIORGIO MOLTENI
core   +1 more source

Synthesis and Antimicrobial Activity of Some New Thiadiazoles, Thioamides, 5-Arylazothiazoles and Pyrimido[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines

Molecules, 2016
A novel series of 1,3,4-thiadiazoles, 5-arylazothiazoles and hexahydropyrimido-[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines were synthesized via reaction of hydrazonoyl halides with each of alkyl carbothioates, carbothioamides and 7-thioxo-5,6,7,8 ...
Abdou O. Abdelhamid, Ibrahim E. El Sayed, Mohamed Z. Hussein, Mangoud M. Mangoud   +3 more
doaj   +1 more source

Mechanistic insights of the copper(I)-catalysed reaction between chlorohydrazones and terminal alkynes [PDF]

, 2023
Deuterium incorporation in the 5-substituted pyrazoles arising from the copper(I)-catalysed reaction between chlorohydrazones and terminal acetylenes suggest the intermediacy of copper(I)-complexed alkynylhydrazones.
Molteni, Giorgio, Ponti, Alessandro, Silvani, Alessandra   +2 more
core   +1 more source

Synthesis and Cytotoxicity Evaluation of Some Novel Thiazoles, Thiadiazoles, and Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones Incorporating Triazole Moiety

Molecules, 2015
Reactions of hydrazonoyl halides and each of methyl 2-(1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)ethylidene)hydrazine-1-carbodithioate and 2-(1-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)ethylidene)hydrazine-1-carbothioamide afforded 2-(1-(5-methyl-1 ...
Sobhi M. Gomha, Sayed A. Ahmed, Abdou O. Abdelhamid   +2 more
doaj   +1 more source

Ultrasound-assisted green synthesis and antimicrobial assessment of 1,3-thiazoles and 1,3,4-thiadiazines

Green Chemistry Letters and Reviews, 2021
In this article, we applied ultrasonic irradiation as an ecofriendly, green, efficient approach for the synthesis of a new 1,3-thiazoles and 1,3,4-thiadiazines under solvent-free conditions.
Sara N. Shabaan, Basma Saad Baaiu, Anhar Abdel-Aziem, Mohamed S. Abdel-Aziz   +3 more
doaj   +1 more source

Synthesis, docking and evaluation of novel fused pyrimidine compounds as possible lead compounds with antibacterial and antitumor activities [PDF]

, 2023
Reaction of a series of hydrazonoyl chlorides with substituted aminopyrimidines afforded good selectivity in most cases leading either to formation of new imidazo[1,2-a]pyrimidine derivatives, or regioisomeric hydrazonamide adducts.
Abu-Teim, Omar S., Al-Reefi, Mariam R, Almasri, Ihab M., Alzaharna, Mazen M., Awadallah, Adel M., Azarah, Jannat N., Beadham, Ian, El-Hallaq, Amany F., Elmanama, Abdelraouf A., Gardiner, John M., Morjan, Rami Y., Raftery, James   +11 more
core   +1 more source

A new convenient synthesis of 3-hetaryl-pyrazolo[5,1-c][1,2,4]triazines

Journal of Advanced Research, 2012
Reactions of enaminones 2 with diazotized 5-amino-3-phenylpyrazole provide a convenient route to 3-[(4,5-disubstituted-pyrazol-3-yl)carbonyl]-pyrazolo[5,1-c][1,2,4]triazines.
Ahmad S. Shawali
doaj   +1 more source

Advances in chemical protein modification. [PDF]

, 2015
Chemical protein modification has emerged as an invaluable tool for the development of modified proteins. The complementary use of both genetic and chemical methods has provided a large toolbox that allows the preparation of almost unlimited protein ...
Bernardes, Gonçalo JL, Boutureira, Omar
core   +2 more sources