Results 21 to 30 of about 39,725 (197)

Photoinduced 1,3‐Dipolar Cycloadditions of Cyclic Enones and 2,5‐Disubstituted Tetrazoles: An Unprecedented Pathway to Polysubstituted Pyrazolines and Pyrazoles

European Journal of Organic Chemistry, Volume 26, Issue 47, December 13, 2023., 2023
1,3‐dipolar cycloaddition of cyclic enones with 2,5‐disubstituted nitrile‐imines obtained by photochemical activation of 2,5‐diaryl substituted tetrazoles leads to the formation of novel pyrazoles and pyrazolines. Reactions can be monitored using UV‐vis absorption and emission measurements.
Chiraz Labassi, Nicolas Fournier‐Le Ray, Fabienne Gauffre, Jean‐Luc Fillaut, Rafik Gatri   +4 more
wiley   +1 more source

Synthetic Routes to Imidates and Their Applications in Organic Transformation: Recent Progress

European Journal of Organic Chemistry, Volume 26, Issue 39, October 16, 2023., 2023
Imidates are important organic intermediates used in several synthetic transformations towards N‐heterocycles, natural products and metal complexes with a potential catalytic effect. Herein, the recent synthetic approaches and diverse applications of imidates were categorized and summarized.
Andriani G. Chaidali, Ioannis N. Lykakis
wiley   +1 more source

Different Synthetic Methods for the Preparation of Triazolopyrimidines and their Biological Profile

ChemistrySelect, Volume 8, Issue 23, June 20, 2023., 2023
This review aims to give a broad overview of the synthetic methods, starting from aminotriazoles and pyrimidines, leading to heterocyclic systems containing the triazolopyrimidine ring and presenting the reactivity of these derivatives. Additionally, we have summarized the most important biological activities.
Achraf Hibot, Asmaa Oumessaoud, Abderrafia Hafid, Mostafa Khouili, Maria Dolors Pujol   +4 more
wiley   +1 more source

Electrochemical Synthesis of Pyrazolines and Pyrazoles via [3+2] Dipolar Cycloaddition

Angewandte Chemie International Edition, Volume 62, Issue 9, February 20, 2023., 2023
Electrochemically initiated [3 2] cycloaddition reactions of readily available and less toxic starting materials enable a facile synthesis of pyrazolines and pyrazoles. Application of a biphasic system and sodium iodide in a dual role as mediator and electrolyte allows for selective reactions with outstanding robustness towards scalability.
Martin Linden, Silja Hofmann, Antonia Herman, Nicole Ehler, Robin M. Bär, Siegfried R. Waldvogel   +5 more
wiley   +1 more source

Synthesis, in-silico studies, and biological evaluation of some novel 3-thiazolyl-indoles as CDK2–inhibitors

Results in Chemistry, 2023
The essential enzyme cyclin-dependent kinase 2 (CDK2) is a promising target for anticancer drug development due to its pivotal role in regulating the cell cycle. This study aimed to synthesize novel 3-thiazolyl-indole derivatives and assess their ability
Sobhi M. Gomha, Magdi E.A. Zaki, Deepika Maliwal, Raghuvir R.S. Pissurlenkar, Mohamed S. Ibrahim, Maher Fathalla, Ahmed M. Hussein   +6 more
doaj   +1 more source

Reactions with hydrazonoyl halides 65: Synthesis of some new 1,3,4-thiadiazoles and triazolino[4,3-a]pyrimidines containing pyrazole moiety [PDF]

, 2011
2,3-Dihydro-1,3,4-thiadiazoles, and triazolino[4,3-a]pyrimidines containing pyrazole moieties were prepared from the reaction of alkyl 2-[1-(4-cyano-1,5-diphenyl-1H-pyrazol-3-yl)ethylidene]hydrazinecarbodithioate and pyrimidine-2-thione derivatives with ...
Fahmi, Abdelgawad Ali, Halim, Karema Noury Mahmoud, Karema Noury Mahmoud Halim, Abdelgawad Ali Fahmi, Abdou Osman Abdelhamid, Abdelhamid, Abdou Osman   +5 more
core   +1 more source

Synthesis and Biological Evaluation of Thiazolyl-Ethylidene Hydrazino-Thiazole Derivatives: A Novel Heterocyclic System

Applied Sciences, 2021
The reaction of 2-(1-(2-(2-(4-methoxybenzylidene)hydrazinyl)-4-methylthiazol-5-yl)ethylidene)hydrazinecarbothioamide with a range of hydrazonoyl chlorides and α-halo-compounds yielded three new series of thiazole derivatives.
Laila A. Al-Mutabagani, Fathy M. Abdelrazek, Sobhi M. Gomha, Ali S. Hebishy, Mohamed S. Abdelfattah, Safaa M. Hassan, Abdelwahed R. Sayed, Mahmoud M. Elaasser   +7 more
doaj   +1 more source

Hydrazonoyl Halides: Their Versatile Biological Activities

The Open Bioactive Compounds Journal, 2009
The various biological activities namely anthelmintic, antiarthropodal, antiviral, antimicrobial, herbicidal, antisarcoptic, acaricidal, insecticidal and miticidal activities exhibited by the hydrazonoyl halides are surveyed. Also, the uses of such halides as pesticides, weed controlling and antihypertensive agents as well as lipoxygenase and cyclo ...
Ahmad S.Shawali, Nevien A.Samy
openaire   +1 more source

Synthesis of New 3-Heteroarylindoles as Potential Anticancer Agents

Molecules, 2016
2-(3-(1H-Indol-3-yl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)-4-substituted-5-(substituted diazenyl)thiazoles and 2-(1H-indol-3-yl)-9-substituted-4,7-disubstituted pyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-5(7H)-ones were synthesized via reaction of ...
Abdou O. Abdelhamid, Sobhi M. Gomha, Nadia A. Abdelriheem, Saher M. Kandeel   +3 more
doaj   +1 more source

Effect of radiation-induced emission of Schottky defects on the formation of colloids in alkali halides [PDF]

, 2003
Formation of vacancy clusters in irradiated crystals is considered taking into account radiation-induced Schottky defect emission (RSDE) from extended defects.
Hartog, H.W. den,, Den Hartog, H W, Vainshtein, D I, Dubinko, [No Value], Vainshtein, DI, Dubinko, V.I.,, Den Hartog, HW, Dubinko, V I, Vainshtein, D.I.,   +8 more
core   +1 more source