Results 11 to 20 of about 39,725 (197)

Hydrazonoyl Chlorides as Precursors for Synthesis of Novel Bis-Pyrrole Derivatives

Molecules, 2016
A convenient synthesis of some novel bis-pyrrole derivatives via hydrazonoyl halides is described. Antimicrobial evaluation of some selected examples of the synthesized products was carried out.
Nabila Abdelshafy Kheder
doaj   +2 more sources

Synthesis and characterization of novel heterocycles based on tetrazine and hydrazonoyl halides [PDF]

European Journal of Chemistry, 2014
The present work describes the preparation and characterization of new pyridazine, thiohydrazonate, bis -pyrazole, bis -triazole and polypyrazoles based on tetrazine and hydrazonoyl halides. The structures of the newly synthesized were elucidated on the basis of their spectral data FT-IR, NMR, Mass and elemental analysis.
Abdelwahed Rashad Sayed, Shar Saad Al-Shihry, Mohsen Abdel-Motaal Gomaa   +2 more
openaire   +3 more sources

Synthesis, Characterization and Molecular Docking of Novel Bioactive Thiazolyl-Thiazole Derivatives as Promising Cytotoxic Antitumor Drug

Molecules, 2015
Reactions of ethylidenethiocarbohydrazide with hydrazonoyl halides gave 1,3-thiazole or 1,3,4-thiadiazole derivatives according to the type of hydrazonoyl halides.
Sobhi M. Gomha, Taher A. Salaheldin, Huwaida M. E. Hassaneen, Hassan M. Abdel-Aziz, Mohammed A. Khedr   +4 more
doaj   +2 more sources

A Novel Synthesis of 1,2,4-Triazolopteridines

Molecules, 2002
Reaction of 1,2-dihydro-2-thioxopteridin-4(3H)-one, 6,7-dimethyl-1,2-dihydro-2-thioxopteridin-4(3H)-one and 6,7-diphenyl-1,2-dihydro-2-thioxopteridin-4(3H)-one with hydrazonoyl halides affords the title compounds in good yields.
Hamdi M. Hassaneen, Manal A. Darwish, Tayseer A. Abdallah   +2 more
doaj   +2 more sources

Synthesis of new functionalized derivatives of indolo[2,3-e][1,2,4]-triazolo-[4,5-b]-1,2,4-triazine [PDF]

Journal of the Serbian Chemical Society, 2013
New functionalized 1,2,4-triazolo-[4,3-b]-1,2,4-triazino-[5,6-b]indole derivatives were synthesized via reaction of the hydrazonoyl halides with 5H-2,3-dihydro-1,2,4-triazino[5,6-b]indole-3-thione or its 3-methylthio derivative.
Gomha Sobhi M., Abdel-Aziz Hatem A.
doaj   +2 more sources

Synthesis of Some New 1,3,4-Thiadiazole, Thiazole and Pyridine Derivatives Containing 1,2,3-Triazole Moiety

Molecules, 2017
In this study, 1-(5-Methyl-1-(p-tolyl)-1H-1,2,3-triazol-4-yl)ethan-1-one, was reacted with Thiosemicarbazide, alkyl carbodithioate and benzaldehyde to give thiosemicarbazone, alkylidenehydrazinecarbodithioate and 3-phenylprop-2-en-1-one-1,2,3-triazole ...
Nadia A. Abdelriheem, Ali M. M. Mohamed, Abdou O. Abdelhamid   +2 more
doaj   +2 more sources

Novel Thiadiazole-Based Molecules as Promising Inhibitors of Black Fungi and Pathogenic Bacteria: In Vitro Antimicrobial Evaluation and Molecular Docking Studies [PDF]

Molecules, 2022
Novel 1,3,4-thiadiazole derivatives were synthesized through the reaction of methyl 2-(4-hydroxy-3-methoxybenzylidene) hydrazine-1-carbodithioate and the appropriate hydrazonoyl halides in the presence of a few drops of diisopropylethylamine.
Huda R. M. Rashdan, Mohamad T. Abdelrahman, Ihsan A. Shehadi, Sara S. El-Tanany, Bahaa A. Hemdan   +4 more
doaj   +2 more sources

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin-Dependent Kinase 4 Inhibitors. [PDF]

ChemistryOpen
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Abolibda TZ, Al-Hussain SA, Farag B, El-Naggar M, Zaki MEA, Alhazmi ESA, Almohammadi ASM, Gomha SM.   +7 more
europepmc   +2 more sources

Concomitant colour polymorphs of (Z)-N-(4-fluorophenyl)-2-oxopropanehydrazonoyl chloride. [PDF]

Acta Crystallogr C Struct Chem
(Z)‐N‐(4‐Fluorophenyl)‐2‐oxopropanehydrazonoyl chloride forms concomitant colour polymorphs, namely, block‐shaped pale‐orange crystals of form I (space group P21/n, Z = 4) and needle‐shaped pale‐yellow crystals of form II (space group P21/c, Z = 4).The title compound, (Z)‐N‐(fluorophenyl)‐2‐oxopropanehydrazonoyl chloride, C9H8ClFN2O, was found to form ...
Müller L, Goddard R, Frohberg P, Seidel RW.   +3 more
europepmc   +2 more sources

Reactions with Hydrazonoyl Halides. Part 21. Reinvestigation of the Reactions of Hydrazonoyl Bromides with 1,1-Dicyanothioacetanilide [PDF]

Journal of Chemical Research, 1999
The reaction of C-(benzoyl) -N- (phenyl) formohydrazonoyl bromide with 1,1-dicyanothioacetanilide was reinvestigated. The product was elucidated on the basis of elemental analysis, spectral data and alternative synthesis. Also, reaction of hydrazonoyl halides with different thioanilides were investigated.
Abdou O. Abdelhamid, Hussein F. Zohdi, Nora M. Rateb   +2 more
openaire   +1 more source