Results 61 to 70 of about 677,906 (386)

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

Long-term efficacy and safety of nalfurafine hydrochloride on pruritus in chronic liver disease patients: Patient-reported outcome based analyses

PLoS ONE, 2017
Background and aim Among various symptoms accompanied with chronic liver disease, pruritus affects the quality of life of patients, causing physical and mental stress, and worsens hepatic function.
Kenya Kamimura, Takeshi Yokoo, Hiroteru Kamimura, Akira Sakamaki, Satoshi Abe, A. Tsuchiya, M. Takamura, H. Kawai, S. Yamagiwa, S. Terai   +9 more
semanticscholar   +1 more source

Scientific Opinion on the safety and efficacy of vitamin B1 (thiamine mononitrate and thiamine hydrochloride) as a feed additive for all animal species based on a dossier submitted by Lohmann Animal Health

EFSA Journal, 2011
Thiamine mononitrate administered via feed and thiamine hydrochloride via feed or water for drinking are safe for the target animals having a wide margin of safety.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Radiolytic studies of cefozopran hydrochloride in the solid state

Electronic Journal of Biotechnology, 2017
Background: The radiation sterilization is one of the best methods for sterilizing vulnerable degradation drugs like cefozopran hydrochloride. Results: Chemical stability of radiosterylized cefozopran hydrochloride, was confirmed by spectrophotometric ...
Przemysław Zalewski, Robert Skibiński, Daria Szymanowska-Powałowska, Hanna Piotrowska, Waldemar Bednarski, Judyta Cielecka-Piontek   +5 more
doaj   +1 more source

Ritodrine-Induced Agranulocytosis: A Case Report and Literature Review

Case Reports in Obstetrics and Gynecology, 2020
Ritodrine hydrochloride is used for preterm labor, although serious side effects, including agranulocytosis, are reported. We report a case of ritodrine hydrochloride-induced agranulocytosis accompanied by bacteremia due to catheter infection.
Atsushi Daimon, Misa Nunode, Takumi Sano, Tomohito Tanaka, Daisuke Fujita, Masahide Ohmichi   +5 more
doaj   +1 more source

Food, Acid Supplementation and Drug Absorption - a Complicated Gastric Mix: a Randomized Control Trial. [PDF]

, 2019
PURPOSE:The purpose of this study was to determine the impact of food on gastric pH and the ability of over the counter betaine hydrochloride (BHCl) acid to reacidify gastric pH after food-induced elevations in gastric pH.
Benet, Leslie Z, Frassetto, Lynda A, Surofchy, Dalga D   +2 more
core  

Calculating Hyperfine Couplings in Large Ionic Crystals Containing Hundreds of QM Atoms: Subsystem DFT is the Key [PDF]

, 2013
We present an application of the linear scaling Frozen Density Embedding (FDE) formulation of subsystem DFT to the calculation of isotropic hyperfine coupling constants (hfccs) of atoms belonging to a guanine radical cation embedded in a guanine ...
Close, David M., Kevorkyants, Ruslan, Pavanello, Michele, Wang, Xiqiao   +3 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Brain targeted oral delivery of doxycycline hydrochloride encapsulated Tween 80 coated chitosan nanoparticles against ketamine induced psychosis: behavioral, biochemical, neurochemical and histological alterations in mice

Drug Delivery, 2017
To develop statistically optimized brain targeted Tween 80 coated chitosan nanoparticulate formulation for oral delivery of doxycycline hydrochloride for the treatment of psychosis and to evaluate its protective effect on ketamine induced behavioral ...
M. Yadav, M. Parle, Nidhi Sharma, Sameer Dhingra, Neha Raina, D. Jindal   +5 more
semanticscholar   +1 more source

Investigations into feline (Felis catus) palatability : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutritional Science at Massey University [PDF]

, 2004
Due to the finicky nature of the domestic cats' feeding habits, palatability is a highly complex area of feline nutrition, but one which is vitally important, with pet owners today selecting a brand based on palatability rather than nutritional value ...
Rutherford, Shay Rebekah
core