Results 11 to 20 of about 21,823 (203)

Effectiveness and safety of combining thiazides with loop diuretics vs. loop diuretics monotherapy in patients with acute decompensated heart failure: A retrospective cohort study. [PDF]

Br J Clin Pharmacol
Aims This study investigated factors associated with and outcomes of combined loop diuretics with hydrochlorothiazide (HCTZ) for acute decompensated heart failure (ADHF). Methods In this retrospective study, adults hospitalized for ADHF and who received intravenous loop diuretics between January 2016 and March 2023 were enrolled.
Hsu CC, Chiu HC, Wung JC, Chou YC, Chang YL, Chou CY, Huang CC.   +6 more
europepmc   +2 more sources

Formulation and Characterisation of a Combination Captopril and Hydrochlorothiazide Microparticulate Dosage Form

Pharmaceutics, 2020
Cardiovascular diseases such as hypertension and cardiac failure in South African children and adolescents are effectively managed long term, using a combination treatment of captopril and hydrochlorothiazide.
Mellisa T. R. Chikukwa, Roderick B. Walker, Sandile M. M. Khamanga   +2 more
doaj   +1 more source

Pharmacoeconomic evaluation of stroke and myocardial infarction prevention in hypertensive patients: Markov model based on the ACCOMPLISH trial

Journal of International Medical Research, 2023
Objective We evaluated the pharmacoeconomics of amlodipine combined with benazepril and hydrochlorothiazide combined with benazepril in the treatment of hypertension using a Markov model to provide an evidence-based reference for clinical drug use ...
Aozi Feng, Weizhao Lin, Li Li, Mengnan Zeng, Jun Lyu   +4 more
doaj   +1 more source

Evaluation and Comparison of Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) as Vectors to Develop Hydrochlorothiazide Effective and Safe Pediatric Oral Liquid Formulations

Pharmaceutics, 2021
The aim of this study was the optimization of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in terms of physicochemical and biopharmaceutical properties, to develop effective and stable aqueous liquid formulations of ...
Paola Mura, Francesca Maestrelli, Mario D’Ambrosio, Cristina Luceri, Marzia Cirri   +4 more
doaj   +1 more source

Hydrochlorothiazide and risk of hearing disorder: a case series

Journal of Medical Case Reports, 2018
Background Hydrochlorothiazide is not known to cause hearing disorder. The Eritrean Pharmacovigilance Centre, however, has received cases of hearing disorder, including irreversible deafness, associated with hydrochlorothiazide. The aim of this study is,
Natnael Belai, Selamawit Gebrehiwet, Yodit Fitsum, Mulugeta Russom   +3 more
doaj   +1 more source

Bioanalytical method development and validation for determination of metoprolol tartarate and hydrochlorothiazide using HPTLC in human plasma

Brazilian Journal of Pharmaceutical Sciences, 2013
A simple, sensitive, rapid and economic chromatographic method has been developed for determination of metoprolol tartarate and hydrochlorothiazide in human plasma using paracetamol as an internal standard.
Ambadas Ranganath Rote, Poonam Ramdas Sonavane   +1 more
doaj   +1 more source

Validated HPTLC methods for determination of some selected antihypertensive mixtures in their combined dosage forms

Bulletin of Faculty of Pharmacy Cairo University, 2014
Simple and selective HPTLC methods were developed for the simultaneous determination of the antihypertensive drugs; carvedilol and hydrochlorothiazide in their binary mixture (Mixture I) and amlodipine besylate, valsartan, and hydrochlorothiazide in ...
Rasha A. Shaalan, Tarek S. Belal, Fawzy A. El Yazbi, Sohila M. Elonsy   +3 more
doaj   +1 more source

The Antihypertensive Efficacy of Chlorthalidone and Telmisartan in Indian Hypertensive Patients who were Uncontrolled with Hydrochlorothiazide and Telmisartan Combination-A Prospective and an Open Label Study [PDF]

Journal of Clinical and Diagnostic Research, 2014
Objective: The primary objective of this study was to evaluate the antihypertensive efficacy of the chlorthalidone and telmisartan combination in Indian hypertensive patients who remained uncontrolled after taking the hydrochlorothiazide and ...
Suresh V Sagarad, Sudha Biradar Kerure, Chaitanya Kumar S, Ramakrishna MR   +3 more
doaj   +1 more source

Interaction and Compatibility Studies in the Development of Olmesartan Medoxomil and Hydrochlorothiazide Formulations under a Real Manufacturing Process

Pharmaceutics, 2022
A drug–drug and drug–excipient interactions and compatibilities study was conducted for two fixed-dose combination (FDC) products containing olmesartan medoxomil (OLM)/hydrochlorothiazide (HCT) 20/12.5 mg and OLM/HCT 40/12.5 mg during their development ...
Mac Arturo Murillo-Fernández, Ernesto Montero-Zeledón, Ariadna Abdala-Saiz, José Roberto Vega-Baudrit, Andrea Mariela Araya-Sibaja   +4 more
doaj   +1 more source

Alterations in Urine Parameters Following One Week of Hydrochlorothiazide Consumption in Hypertensive Individuals [PDF]

Translational Research in Urology
Introduction: Hydrochlorothiazide is widely prescribed for managing hypertension. Despite its extensive use, there is a significant lack of scientific literature addressing its impact on 24-hour urine parameters.
Reza Valipour, Behzad Narouie, Sajedeh Jadidi, Negar Radpour, Hamidreza Momeni, Hamidreza Rouientan, Sara Saygin   +6 more
doaj   +1 more source