Results 11 to 20 of about 35,744 (252)

Binding of hydrochlorothiazide to erythrocytes.

Journal of Pharmacobio-Dynamics, 1989
Hydrochlorothiazide (HCT) was administered orally to healthy volunteers and intravenously to rabbits. HCT concentrations in plasma (Cp) and erythrocytes (Ce) were determined by a high-performance liquid chromatographic method. Ce was about 9-fold that of Cp 24 h after the administration to volunteers, and 8-fold 6 h after the administration to rabbits.
Masaru Yamazaki, Yoshifumi Fukuhara, Hajime Nakahama, Yoshimasa Orita, Kazuhisa Tanabe, Teruaki Okuda, Soichi Itoh   +6 more
openaire   +5 more sources

Simultaneous analysis of aliskiren and hydrochlorothiazide in pharmaceutical preparations and spiked human plasma by HPTLC [PDF]

Journal of Taibah University for Science, 2017
A simple, selective and precise method based on HPTLC has been developed for the simultaneous determination of aliskiren and hydrochlorothiazide in a fixed-dose tablet formulation and human plasma.
Bhatt, Nejal M., Chavada, Vijay D., Pandya, Jui J., Sanyal, Mallika, Sharma, Primal, Shrivastav, Pranav S.   +5 more
core   +4 more sources

Is the fixed-dose combination of telmisartan and hydrochlorothiazide a good approach to treat hypertension? [PDF]

Vascular Health and Risk Management, 2007
Blockade of the renin-angiotensin system with selective AT1 receptor antagonists is recognized as an effective mean to lower blood pressure in hypertensive patients.
Burnier, M., Maillard, M.P.
core   +2 more sources

Bioequivalence and Food Effect Assessment of Two Fixed-Dose Combination Formulations of Telmisartan-Hydrochlorothiazide Tablets in Chinese Healthy Subjects. [PDF]

Clin Transl Sci
This study assessed the bioequivalence and food effect of two fixed‐dose combination (FDC) formulations of telmisartan‐hydrochlorothiazide tablets (telmisartan 40 mg, hydrochlorothiazide 12.5 mg) in healthy Chinese subjects.
Hu M, Yang M, Zhang S, Li J, Pang H, Pei Y, Guo C, Wang X.   +7 more
europepmc   +2 more sources

Long-term hydrochlorothiazide use and risk of cutaneous neoplasms

Current Medical Issues, 2021
Background: Hydrochlorothiazide is a diuretic commonly used in the treatment of hypertension. Recently, there have been published reports of hydrochlorothiazide-induced cutaneous neoplasms among Caucasians.
Heber Rew Bright, Sujith J Chandy, Renu George, Meera Thomas, Pradeep Rajkumar, Anju George   +5 more
doaj   +1 more source

Chronic Use of Hydrochlorothiazide and Risk of Skin Cancer in Caucasian Adults: A PharmLines Initiative Inception Cohort Study

Acta Dermato-Venereologica, 2023
Photosensitizing properties of hydrochlorothiazide may increase skin cancer risk. To date, study findings on the association between hydrochlorothiazide use and skin cancer risk are inconsistent, notably regarding confounding and dose-response.
Marjolijn S. Haisma, Nathalie Greven, Mathanhy Logendran, Jens Bos, Bert v.d. Vegt, Barbara Horváth, Stijn de Vos, Geertruida H. de Bock, Eelko Hak, Emőke Rácz   +9 more
doaj   +1 more source

A Rare Case of Pulmonary Edema Secondary to Hydrochlorothiazide Use. [PDF]

Case Rep Crit Care
Noncardiogenic pulmonary edema has been reported as a rare adverse reaction of hydrochlorothiazide. Symptoms can develop acutely after medication ingestion, and patients may present acutely ill. The mechanism by which hydrochlorothiazide causes pulmonary
Chen EJ, Hayrapetian L, Frishe K.
europepmc   +2 more sources

Chemometric Methods for Simultaneous Determination of Candesartan Cilexetil and Hydrochlorothiazide in Binary Combinations

Journal of Analytical Methods in Chemistry, 2023
Simple, accurate, precise, and cost-effective chemometric techniques for the measurement of candesartan cilexetil and hydrochlorothiazide in synthetic mixtures were improved and validated.
Diyar Salahuddin Ali
doaj   +1 more source

Simultaneous Determination of Candesartan and Hydrochlorothiazide in Human Plasma by HPLC-MS/MS

Разработка и регистрация лекарственных средств, 2021
Introduction. Combined drugs have the greatest efficacy and safety in arterial hypertension treatment. The combination of candesartan and hydrochlorothiazide (AT1-receptor antagonist and a thiazide diuretic, respectively) provides high efficiency of ...
P. K. Karnakova, T. N. Komarov, O. A. Archakova, D. S. Shchelgacheva, A. A. Aleshina, N. S. Bagaeva, P. A. Karpova, I. E. Shohin   +7 more
doaj   +1 more source

Aspects of efficacy, safety and adherence to antihypertensive therapy with single pill combinations of valsartan, amlodipine and hydrochlorothiazide (Vamloset® and Co-Vamloset) in patients with 2 and 3 grade of arterial hypertension in the Russian clinical study VICTORY II

Системные гипертензии, 2021
Aim. To assess the efficacy and safety of Vamloset (amlodipine/valsartan 5/80, 5/160, 10/160 mg) and Co-Vamloset (amlodipine/valsartan/hydrochlorothiazide 10/160/12.5, 10/160/25 mg) in achieving the target levels of blood pressure (BP) in patients with ...
Irina E. Chazova, Tamila V. Martynyuk, Oleg V. Rodnenkov, Shurat B. Gorieva, Anatolii N. Rogoza, Mikhail V. Arkhipov, Yury I. Grinshtein, Olga D. Ostroumova, Albert S. Galyavich, Oxana P. Rotar’, Larisa A. Khaisheva, Tatiana R. Kameneva   +11 more
doaj   +1 more source