Results 41 to 50 of about 35,149 (271)

Alterations in Urine Parameters Following One Week of Hydrochlorothiazide Consumption in Hypertensive Individuals [PDF]

Translational Research in Urology
Introduction: Hydrochlorothiazide is widely prescribed for managing hypertension. Despite its extensive use, there is a significant lack of scientific literature addressing its impact on 24-hour urine parameters.
Reza Valipour, Behzad Narouie, Sajedeh Jadidi, Negar Radpour, Hamidreza Momeni, Hamidreza Rouientan, Sara Saygin   +6 more
doaj   +1 more source

Use of hydrochlorothiazide and risk of skin cancer: a nationwide Taiwanese case–control study

British Journal of Cancer, 2019
The antihypertensive agent hydrochlorothiazide has been associated with increased risks of non-melanoma skin cancer (NMSC) and possibly some melanoma subtypes. Previous studies were, however, conducted in predominantly Caucasian populations. We therefore
A. Pottegård, S. Pedersen, S. Schmidt, Chaw-Ning Lee, Chao-Kai Hsu, T. Liao, S. Shao, E. Lai   +7 more
semanticscholar   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

USE OF FIXED COMBINATIONS OF RAMIPRIL AND HYDROCHLOROTHIAZIDE IN PATIENTS WITH ARTERIAL HYPERTENSION AND HIGH OR VERY HIGH CARDIOVASCULAR RISK (OPTIMIST 2 STUDY): RESULTS OF THE NONCOMPARATIVE STUDY

Рациональная фармакотерапия в кардиологии, 2016
Aim. To evaluate efficacy and safety of treatment with fixed combination of ramipril and hydrochlorothiazide in patients with arterial hypertension (HT) 2-3 degree and high or very high cardiovascular risk in clinical practice.
I. A. Velizhanina, L. I. Gapon, E. S. Velizhanina, A. V. Rudakov, T. S. Zhupanova   +4 more
doaj   +1 more source

First Line CombinAtion Therapy in the Treatment of Stage II and III Hypertension (FLASH)

Frontiers in Cardiovascular Medicine, 2020
Background: Lowering blood pressure (BP) leads to reduced risk of stroke, myocardial infarction, and cardiovascular mortality. Single-pill combination therapies may deliver better BP control than increasing the dose of monotherapies or using more drugs ...
David Spirk, Sarah Noll, Michel Burnier, Stefano Rimoldi, Georg Noll, Georg Noll, Isabella Sudano, Isabella Sudano   +7 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source

Highly sensitive determination of methyldopa and hydrochloro­thiazide using CoMoO4 nanosheets-modified screen-printed electrode

Journal of Electrochemical Science and Engineering
A novel screen-printed electrode (SPE) modified by CoMoO4 nanosheets (CoMoO4 NSs) was designed to analyse hydrochlorothiazide. Cyclic voltammetry, chronoamprometry and differential pulse voltammetry using the developed electrode were performed to ...
Shams B. Ali
doaj   +1 more source

Acute hepatocellular and cholestatic injury during therapy with hydrochlorothiazide - clinicohistopathologic findings: a case report

Journal of Medical Case Reports, 2010
Introduction Hydrochlorothiazide and thiazide-like diuretics are considered first-line drugs for initial therapy in uncomplicated arterial hypertension. Acute cholecystitis is a well-known complication during treatment with thiazide, and these drugs are ...
Grilli Elisabetta, Capone Alessandro, Pieri Stefano, Falasca Laura, Baiocchini Andrea, Del Nonno Franca, Taglietti Fabrizio, Chinello Pierangelo, Petrosillo Nicola   +8 more
doaj   +1 more source

Comparative efficacy and safety of chlorthalidone and hydrochlorothiazide—meta-analysis

Journal of Human Hypertension, 2019
Hypertension is a complex syndrome of multiple hemodynamic, neuroendocrine, and metabolic abnormalities. The goals of treatment in hypertension are to optimally control high blood pressure and to reduce associated cardiovascular morbidity and mortality ...
S. Dineva, K. Uzunova, V. Pavlova, Elena Filipova, K. Kalinov, T. Vekov   +5 more
semanticscholar   +1 more source