Results 51 to 60 of about 16,311 (178)

A Rare Case of Pulmonary Edema Secondary to Hydrochlorothiazide Use

Case Reports in Critical Care
Noncardiogenic pulmonary edema has been reported as a rare adverse reaction of hydrochlorothiazide. Symptoms can develop acutely after medication ingestion, and patients may present acutely ill. The mechanism by which hydrochlorothiazide causes pulmonary
Evan J. Chen, Laurie Hayrapetian, Katherine Frishe   +2 more
doaj   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2429-2442, August 2026.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman, Erik M. Donker, Jelle Tichelaar, on behalf of the CP4T programme   +3 more
wiley   +1 more source

Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundThiazide and thiazide‐like diuretics are first‐line medications for treating uncomplicated hypertension. However, their use has been associated with adverse metabolic events, including hyperglycemia and incident diabetes mellitus, with ...
Sonal Singh, Caitrin W. McDonough, Yan Gong, Wael A. Alghamdi, Meghan J. Arwood, Salma A. Bargal, Leanne Dumeny, Wen‐Yi Li, Mai Mehanna, Bradley Stockard, Guang Yang, Felipe A. de Oliveira, Natalie C. Fredette, Mohamed H. Shahin, Kent R. Bailey, Amber L. Beitelshees, Eric Boerwinkle, Arlene B. Chapman, John G. Gums, Stephen T. Turner, Rhonda M. Cooper‐DeHoff, Julie A. Johnson   +21 more
doaj   +1 more source

Optimization of Newly Diagnosed Hypertension and Type II Diabetes Mellitus Before Myomectomy for Symptomatic Uterine Leiomyoma

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Severe but newly diagnosed cardiometabolic derangements do not preclude safe myomectomy. Structured, time‐limited optimization with multidisciplinary input allows surgery to proceed once cardiovascular risk is controlled, even if glycemic targets remain imperfectly met.
Orji Uguru Williams, Henry Eziefule Nwankwo, Ogodobiri Serena Tamarauemomoemi, Nnaji Chima Celestine, Eze Harrison Chima, Charles Caring Chihoterum   +5 more
wiley   +1 more source

Utilization of Localized Surface Plasmon Resonance of Silver Nanoparticles for ‎the Spectrophotometric Estimation of Amlodipine and Hydrochlorothiazide

مجلة بغداد للعلوم
A potent long-acting calcium channel blockers is amlodipine. Patient with high blood pressure can take it to treat high blood pressure, angina pectoris, and reduce the risk of stroke.
Rasul Jameel Ali , Lazeeza Sattar Omer , Nagham Nadhim Habeeb , Asmaa Ghanim Dawood   +3 more
doaj   +1 more source

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 510-519, August 2026.
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley   +1 more source

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 8, Page 1478-1491, August 2026.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Pharmaceutical Composition of Hydrochlorothiazide:β-Cyclo-dextrin: Preparation by Three Different Methods, Physico-Chemical Characterization and In Vivo Diuretic Activity Evaluation

Molecules, 2011
Hydrochlorothiazide is a common diuretic antihypertensive drug of the thiazide family. Its poor aqueous solubility is one of the reasons for its limited bioavailability after oral administration.
Maria Arlete Silva Pires, Robson Augusto Souza dos Santos, Rubén Dario Sinisterra   +2 more
doaj   +1 more source

Upper Urinary Tract Stone Disease: Practical Guidance for Early Assessment and Management

Trends in Urology &Men's Health, Volume 17, Issue 4, August 2026.
ABSTRACT Upper urinary tract stone disease is a common urological condition with high recurrence rates and a significant healthcare burden. Many patients initially present in community or primary care settings, where early assessment and triage influence patient safety, referral timing and subsequent urological management.
Matthew Kwon, Avi Raman
wiley   +1 more source

Optimization of the Production Process and Product Quality of Titanate Nanotube–Drug Composites

Nanomaterials, 2019
Recently, there has been an increasing interest in the application of nanotubular structures for drug delivery. There are several promising results with carbon nanotubes; however, in light of some toxicity issues, the search for alternative materials has
Yasmin Ranjous, Géza Regdon, Klára Pintye-Hódi, Tamás Varga, Imre Szenti, Zoltán Kónya, Tamás Sovány   +6 more
doaj   +1 more source