Results 1 to 10 of about 11,446 (196)

Telmisartan and cardioprotection

Vascular Health and Risk Management, 2011
Philippe R Akhrass, Samy I McFarlaneState University of New York, Downstate Medical Center, Brooklyn, NY, USAAbstract: Cardiovascular risk reduction has been the target of several large clinical trials in the last decade.
McFarlane S
core   +6 more sources

Single-Cell Transcriptomics Reveals Immune Modulation by Telmisartan in Colorectal Cancer [PDF]

Cells
Telmisartan, an angiotensin II type 1 receptor blocker with established anti-inflammatory and antihypertensive properties, has been reported to inhibit tumor cell proliferation, yet its impact on the tumor immune microenvironment remains poorly ...
Jinxin Li, Decao Yang, Xiaoyue Wang, Runqing Ju, Shaomeng Chen, Jingyi Zhao, Jiaxing Xu, Jiaxin Chen, Jiayu Ye, Baohui Xu, Qianqian Yin, Yan Wang   +11 more
doaj   +2 more sources

Telmisartan for treatment of Covid-19 patients: An open multicenter randomized clinical trial

EClinicalMedicine, 2021
Background: Angiotensin receptor blockers (ARBs), such as telmisartan, have been postulated to treat Covid-19-induced lung inflammation. Methods: This is a parallel-group, randomized, two-arm, open-label, adaptive, multicenter superiority trial with 1:1 ...
Maria Victoria Salgado, Ignacio Davolos, Ignacio Fernández Criado   +2 more
exaly   +3 more sources

Immune pleiotropic effect of telmisartan in arterial hypertension

Медицинская иммунология, 2022
Arterial hypertension (AH) is among the life-threatening diseases and requires permanent antihypertensive therapy, including telmisartan. However, the effect of telmisartan upon systemic interleukin profile in elderly hypertensive patients requires ...
N. M. Agarkov, K. F. Makkonen, A. A. Titov, D. N. Belchikova, L. V. Kolpina   +4 more
doaj   +3 more sources

Incidence of adverse events with telmisartan compared with ACE inhibitors: evidence from a pooled analysis of clinical trials

Patient Preference and Adherence, 2011
Giuseppe Mancia1, Helmut Schumacher21Universita degli Studi Milano-Bicocca, Ospedale San Gerardo di Monza, Milan, Italy; 2Boehringer Ingelheim Pharma GmbH and Co KG, Ingelheim, GermanyAbstract: Telmisartan is indicated for the prevention of ...
Mancia G, Schumacher H
doaj   +2 more sources

Targeting AT1 receptors with telmisartan protects SH-SY5Y cells from 6-OHDA induced Parkinsonian neurotoxicity [PDF]

Scientific Reports
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by oxidative stress, neuroinflammation, and α-synuclein accumulation.
Omer Lutfi Gundogdu, Feyza Burul, Elif Tugce Akyol, Ufuk Okkay, Fatma Yesilyurt, Fatih Burak Yildiz, Irmak Ferah Okkay, Mustafa Ozkaraca, Ahmet Hacimuftuoglu   +8 more
doaj   +2 more sources

Telmisartan Loaded Nanofibers Enhance Re-Endothelialization and Inhibit Neointimal Hyperplasia

Pharmaceutics, 2021
Stent implantation impairs local endothelial function and may be associated with subsequent adverse cardiovascular events. Telmisartan, an angiotensin II receptor blocker that has unique peroxisome proliferator-activated-receptor-gamma-mediated effects ...
Chen-Hung Lee, Kuo-Sheng Liu, Julien George Roth, Kuo-Chun Hung, Yen-Wei Liu, Shin-Huei Wang, Chi-Ching Kuo, Shih-Jung Liu   +7 more
doaj   +2 more sources

Development of telmisartan in the therapy of spinal cord injury: pre-clinical study in rats

Drug Design, Development and Therapy, 2015
Chien-Min Lin,1,* Jo-Ting Tsai,2,* Chen Kuei Chang,1 Juei-Tang Cheng,3 Jia-Wei Lin11Department of Neurosurgery, 2Department of Radiation Oncology, Shuang Ho Hospital-Taipei Medical University, 3Institute of Medical Science, College of Health Science ...
Lin CM, Tsai JT, Chang CK, Cheng JT, Lin JW   +4 more
doaj   +1 more source

Efficacy and Safety of Triple Therapy With Telmisartan, Amlodipine, and Rosuvastatin in Patients With Dyslipidemia and Hypertension: The Jeil Telmisartan, Amlodipine, and Rosuvastatin Randomized Clinical Trial

Clinical Therapeutics, 2019
Purpose: Fixed-dose combination therapy with telmisartan, amlodipine, and rosuvastatin is needed in patients with hypertension and dyslipidemia for better adherence and cost-effectiveness than free-equivalent combination therapies.
, Han Saem Jeong, Jin-Man Cho
exaly   +2 more sources

Angiotensin receptor blocker telmisartan suppresses renal gluconeogenesis during starvation

Diabetes, Metabolic Syndrome and Obesity, 2015
Akihiro Tojo, Saaya Hatakeyama, Satoshi Kinugasa, Masaomi Nangaku Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan Abstract: The kidney plays an important role in gluconeogenesis during starvation.
Tojo A, Hatakeyama S, Kinugasa S, Nangaku M   +3 more
doaj   +1 more source