Results 11 to 20 of about 12,197 (188)

Telmisartan and cardioprotection

Vascular Health and Risk Management, 2011
Cardiovascular risk reduction has been the target of several large clinical trials in the last decade. As the activation of the renin-angiotensin-aldosterone system (RAAS) plays a central role in the pathogenesis of atherosclerosis and cardiovascular disease, RAAS blockade has been suggested to be among the most efficient cardioprotective interventions,
Akhrass,Philippe R, McFarlane,Samy I
openaire   +6 more sources

Incidence of adverse events with telmisartan compared with ACE inhibitors: evidence from a pooled analysis of clinical trials [PDF]

Patient Preference and Adherence, 2011
Giuseppe Mancia1, Helmut Schumacher21Universita degli Studi Milano-Bicocca, Ospedale San Gerardo di Monza, Milan, Italy; 2Boehringer Ingelheim Pharma GmbH and Co KG, Ingelheim, GermanyAbstract: Telmisartan is indicated for the prevention of ...
Mancia G, Schumacher H
doaj   +1 more source

Immune pleiotropic effect of telmisartan in arterial hypertension [PDF]

Медицинская иммунология, 2022
Arterial hypertension (AH) is among the life-threatening diseases and requires permanent antihypertensive therapy, including telmisartan. However, the effect of telmisartan upon systemic interleukin profile in elderly hypertensive patients requires ...
N. M. Agarkov, K. F. Makkonen, A. A. Titov, D. N. Belchikova, L. V. Kolpina   +4 more
doaj   +2 more sources

Development of telmisartan in the therapy of spinal cord injury: pre-clinical study in rats

Drug Design, Development and Therapy, 2015
Chien-Min Lin,1,* Jo-Ting Tsai,2,* Chen Kuei Chang,1 Juei-Tang Cheng,3 Jia-Wei Lin11Department of Neurosurgery, 2Department of Radiation Oncology, Shuang Ho Hospital-Taipei Medical University, 3Institute of Medical Science, College of Health Science ...
Lin CM, Tsai JT, Chang CK, Cheng JT, Lin JW   +4 more
doaj   +1 more source

Angiotensin receptor blocker telmisartan suppresses renal gluconeogenesis during starvation

Diabetes, Metabolic Syndrome and Obesity, 2015
Akihiro Tojo, Saaya Hatakeyama, Satoshi Kinugasa, Masaomi Nangaku Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan Abstract: The kidney plays an important role in gluconeogenesis during starvation.
Tojo A, Hatakeyama S, Kinugasa S, Nangaku M   +3 more
doaj   +1 more source

Telmisartan Loaded Nanofibers Enhance Re-Endothelialization and Inhibit Neointimal Hyperplasia

Pharmaceutics, 2021
Stent implantation impairs local endothelial function and may be associated with subsequent adverse cardiovascular events. Telmisartan, an angiotensin II receptor blocker that has unique peroxisome proliferator-activated-receptor-gamma-mediated effects ...
Chen-Hung Lee, Kuo-Sheng Liu, Julien George Roth, Kuo-Chun Hung, Yen-Wei Liu, Shin-Huei Wang, Chi-Ching Kuo, Shih-Jung Liu   +7 more
doaj   +2 more sources

Telmisartan is effective to ameliorate metabolic syndrome in rat model – a preclinical report

Diabetes, Metabolic Syndrome and Obesity, 2018
Kai-Chun Cheng,1,* Yingxiao Li,1,2,* Wei-Ting Chang,2,3 Feng Yu Kuo,4 Zhih-Cherng Chen,3,5 Juei-Tang Cheng2,6 1Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan ...
Cheng KC, Li Y, Chang WT, Kuo FY, Chen ZC, Cheng JT   +5 more
doaj   +1 more source

Progress in Synthesis and Pharmacology of Telmisartan. [PDF]

Chem Biodivers
Telmisartan is a benzimidazole derivative and a well‐known drug to treat hypertension. This review provides synthesis and understanding of telmisartan as an antihypertensive drug through two mechanisms of actions: RAAS inhibitor and PPARγ receptor. Effective repurposing of this drug for various diseases like chronic kidney illness, diabetes, fatty ...
Megha, Srivastava R, Singh R.
europepmc   +2 more sources

Is the fixed-dose combination of telmisartan and hydrochlorothiazide a good approach to treat hypertension?

Vascular Health and Risk Management, 2007
Marc P Maillard, Michel BurnierService of Nephrology, Department of Internal Medicine, Lausanne University Hospital, SwitzerlandAbstract: Blockade of the renin-angiotensin system with selective AT1 receptor antagonists is recognized as an effective mean ...
Marc P Maillard, Michel Burnier
doaj   +1 more source

Efficacy of Telmisartan in MASLD/NAFLD: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Endocrinol Diabetes Metab
Evidence from six randomized controlled trials indicates that telmisartan offers modest glycemic benefit but does not consistently improve metabolic, biochemical, or histological outcomes in MASLD/NAFLD, highlighting the need for larger, well‐designed clinical trials.
Shojaei S, Shekouh D, Mousavi A, Rostamipourfard S, Karami S, Azadnik S, Nozhat S, Mirhosseini SA, Hashemi E, Fatima N, Hassanabad AF, Borjzadehgashtaseb M, Arzhangzadeh A.   +12 more
europepmc   +2 more sources