Results 1 to 10 of about 48,105 (216)
Comparative Efficacy of Angiotensin II Type 1 Receptor Blockers Against Ventilator‐Induced Diaphragm Dysfunction in Rats [PDF]
Clinical and Translational Science, 2021 Mechanical ventilation (MV) is a life‐saving intervention for many critically ill patients. Unfortunately, prolonged MV results in the rapid development of inspiratory muscle weakness due to diaphragmatic atrophy and contractile dysfunction (termed ...
Stephanie E. Hall +8 more
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Angiotensin II type 1 receptor blockers increase tolerance of cells to copper and cisplatin [PDF]
Microbial Cell, 2014 The human pathology Wilson disease (WD) is characterized by toxic copper (Cu) accumulation in brain and liver, resulting in, among other indications, mitochondrial dysfunction and apoptosis of hepatocytes.
Pieter Spincemaille +8 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Renin‐angiotensin aldosterone system (RAAS) inhibitor—COVID‐19 studies, observational in design, appear to use biased methods that can distort the interaction between RAAS inhibitor use and COVID‐19 risk. This study assessed the extent of bias
Jordan Loader +3 more
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Physiological Reports, 2021 Cognitive impairment has been known as a common consequence of brain inflammation. Long‐term potentiation (LTP), the generally accepted cellular mechanism for memory formation in the mammalian brain, has been shown to be suppressed by inflammation ...
Mahmoud Hosseini +2 more
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Receptor Interactions of Angiotensin II and Angiotensin Receptor Blockers—Relevance to COVID-19
Biomolecules, 2021 Angiotensin II (Ang II) may contain a charge relay system (CRS) involving Tyr/His/carboxylate, which creates a tyrosinate anion for receptor activation. Energy calculations were carried out to determine the preferred geometry for the CRS in the presence ...
Graham J. Moore +6 more
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Association Between Angiotensin II Receptor Blockers and the Risk of Lung Cancer Among Patients With Hypertension From the Korean National Health Insurance Service-National Health Screening Cohort [PDF]
Journal of Preventive Medicine and Public Health, 2020 Objectives: The objective of this study was to estimate the risk of lung cancer in relation to angiotensin II receptor blocker (ARB) use among patients with hypertension from the Korean National Health Insurance Service-National Health Screening Cohort ...
Sungji Moon +3 more
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Angiotensin Receptor Blocker (ARB): Is it Effective to Prevent Cerebral Malaria? [PDF]
Afro-Egyptian Journal of Infectious and Endemic DiseasesCerebral malaria is a severe complication of plasmodium falciparum infection with 15-25% mortality rates. Sequestration of infected red blood cells disrupts the blood brain barried leading to irreversible brain damage, impacting quality of life.
I Gusti Ayu Hiranandini Prawista +6 more
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The fourth-generation Calcium channel blocker: Cilnidipine
Indian Heart Journal, 2013 Several classes of antihypertensive agents have been in clinical use, including diuretics, α-blockers, β-blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin II type 1 receptor blockers (ARB), and organic calcium channel blockers (CCBs).
K. Sarat Chandra, G. Ramesh
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Angiotensin II Type I Receptor (AT1R): The Gate towards COVID-19-Associated Diseases
Molecules, 2022 The binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein to its cellular receptor, the angiotensin-converting enzyme 2 (ACE2), causes its downregulation, which subsequently leads to the dysregulation of the renin–
George El-Arif +10 more
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International Journal of Infectious Diseases, 2020 ACE2 is a receptor of entry of SARS-CoV-2 into the host cells, and its upregulation has been implicated in increasing susceptibility of individuals to this infection.
Ashwini Shete
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