Results 21 to 30 of about 9,019 (158)

Telmisartan Exerts Anti-Tumor Effects by Activating Peroxisome Proliferator-Activated Receptor-γ in Human Lung Adenocarcinoma A549 Cells

Molecules, 2014
Telmisartan, a member of the angiotensin II type 1 receptor blockers, is usually used for cardiovascular diseases. Recent studies have showed that telmisartan has the property of PPARγ activation.
Juan Li, Lin Chen, Ping Yu, Bin Liu, Jiang Zhu, Ye Yang   +5 more
doaj   +1 more source

In a subgroup of high-risk Asians, telmisartan was non-inferior to ramipril and better tolerated in the prevention of cardiovascular events. [PDF]

PLoS ONE, 2010
Results of the recently published ONTARGET study (The Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial) showed that telmisartan (80 mg/day) was non-inferior to ramipril (10 mg/day) in reducing cardiovascular events ...
Antonio L Dans, Koon Teo, Peggy Gao, Jyh-Hong Chen, Kim Jae-Hyung, Khalid Yusoff, Suphachai Chaithiraphan, Jun Zhu, Liu Lisheng, Salim Yusuf, Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial Investigators   +10 more
doaj   +1 more source

Dialysis-associated hypertension treated with Telmisartan--DiaTel: a pilot, placebo-controlled, cross-over, randomized trial.

PLoS ONE, 2013
UnlabelledTreatment of hypertension in hemodialysis (HD) patients is characterised by lack of evidence for both the blood pressure (BP) target goal and the recommended drug class to use.
Matthias Huber, Till Treutler, Peter Martus, Antje Kurzidim, Reinhold Kreutz, Joachim Beige   +5 more
doaj   +1 more source

Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet

Journal of Pharmacological Sciences, 2016
Although telmisartan, an angiotensin II receptor blocker (ARB), has an agonistic action for proliferator-activated receptor (PPAR)-γ in vitro, it remains to be determined whether telmisartan exerts such an action in vivo using a non-toxic dose (
Hayato Yanagihara, Kentaro Ushijima, Yusuke Arakawa, Ken-ichi Aizawa, Akio Fujimura   +4 more
doaj   +1 more source

Telmisartan Loaded Nanofibers Enhance Re-Endothelialization and Inhibit Neointimal Hyperplasia

Pharmaceutics, 2021
Stent implantation impairs local endothelial function and may be associated with subsequent adverse cardiovascular events. Telmisartan, an angiotensin II receptor blocker that has unique peroxisome proliferator-activated-receptor-gamma-mediated effects ...
Chen-Hung Lee, Kuo-Sheng Liu, Julien George Roth, Kuo-Chun Hung, Yen-Wei Liu, Shin-Huei Wang, Chi-Ching Kuo, Shih-Jung Liu   +7 more
doaj   +1 more source

Planning and Evaluation of Bioequivalence Studies of Telmisartan Generic Drug Products

Разработка и регистрация лекарственных средств, 2019
Introduction. Telmisartan is a modern antihypertensive drug, from the group of angiotensin II receptor antagonists, which, recently, has been the purpose of the development and registration of generic drug.
A. L. Khokhlov, D. P. Romodanovsky, A. E. Miroshnikov   +2 more
doaj   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Bioequivalence and Food Effect Assessment of Two Fixed‐Dose Combination Formulations of Telmisartan‐Hydrochlorothiazide Tablets in Chinese Healthy Subjects

Clinical and Translational Science
This study assessed the bioequivalence and food effect of two fixed‐dose combination (FDC) formulations of telmisartan‐hydrochlorothiazide tablets (telmisartan 40 mg, hydrochlorothiazide 12.5 mg) in healthy Chinese subjects.
Minwan Hu, Man Yang, Shuyu Zhang, Jiangfan Li, Hongxian Pang, Yingzi Pei, Chao Guo, Xuhong Wang   +7 more
doaj   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

2-(4-{[4-Methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl] methyl} phenyl) benzoic acid as green corrosion inhibitor for mild steel in 1 M hydrochloric acid

Ain Shams Engineering Journal, 2018
Present study describes the inhibition property of benzo 1,3-diazol 2-(4-{[4-Methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl] methyl} phenyl) benzoic acid (Telmisartan, Cresar-H) on mild steel corrosion in 1 M HCl using ...
Chandrabhan Verma, M.A. Quraishi, Neeraj Kumar Gupta   +2 more
doaj   +1 more source