Results 61 to 70 of about 16,311 (178)

Towards a Safe and Effective Lithium Therapeutic Range for Older Adults With Bipolar Disorder: An ISBD Task Force Systematic Review

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objectives Lithium is recommended as the first‐line maintenance treatment for older adults with bipolar disorder (OABD). However, age‐related reduction in renal clearance, heightened sensitivity to adverse effects, and drug interactions increase the risk of toxicity and necessitate lower therapeutic serum levels in this population.
Paula V. Nunes, Andrew T. Olagunju, Debbie Zittema, Astha Dhyani, Lei Fu, Peijun Chen, Laura Montejo, Gabriel R. Fries, Lars V. Kessing, Eduard Vieta, Orestes V. Forlenza, Annemieke Dols, Hilary P. Blumberg, Lisa T. Eyler, Kenneth I. Shulman, on behalf of the International Society for Bipolar Disorders (ISBD) Older Adults with Bipolar Disorder (OABD) Lithium Workgroup Task Force   +15 more
wiley   +1 more source

Australian Guideline for the Identification and Management of Hypertension in Children and Adolescents

Journal of Paediatrics and Child Health, EarlyView.
N. G. Larkins, T. Medley, A. Black, K. A. Bolton, S. Chaturvedi, M. Clark, G. M. Gabb, J. P. Glenning, C. Grimes, R. C. Huang, A. Hyland, C. Jeffries‐Stokes, L. Kalman, S. Kaul, S. Kim, S. McTaggart, R. Kowalski, S. X. Li, S. McNab, D. Metz, A. S. Mihailidou, J. Monin, M. Nelson, M. Pathak, D. Roebuck, M. P. Schlaich, R. Sleaby, C. Quinlan, J. P. Mynard   +28 more
wiley   +1 more source

Exploring Risks of Adverse Drug Events From Single Drug to Three‐Drug Combination

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Use of three‐drug combinations is common and could increase the risk of adverse drug events (ADEs). Signals of ADEs from three‐drug combinations could be identified from real‐world data, and the risks of ADEs from single drug exposure to three‐drug combination exposure could be illustrated by a graphic model.
Yi Shi, Anna Sun, Chien‐Wei Chiang, Yuedi Yang, Katherine M. Hunold, Jing Xu, Mu Shan, Allison Lu, Massimiliano Russo, Jeffrey M. Caterino, Michael T. Eadon, Lang Li, Jing Su, Macarius Donneyong, Pengyue Zhang   +14 more
wiley   +1 more source

Temporal Drivers of Opioid‐Related ED Visits: An Ensemble Machine Learning Study With Consensus‐Based Feature Attribution

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Identification of modifiable risk factors for prescription opioid use disorder (OUD)‐related emergency department (ED) visits (ICD‐10 F11.xx) is a clinical priority; however, most published models remain cross‐sectional and lack pharmacogenomic (PGx) enrichment or dual‐method feature confirmation. Using Virginia All‐Payer Claims Database (APCD)
R. Jerome Dixon, Elvin T. Price
wiley   +1 more source

Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation

Journal of Pharmacy and Bioallied Sciences, 2010
Aim : To develop a simple, accurate, rapid and precise UV spectrophotometric method for the estimation of atenolol in combination with losartan potassium and hydrochlorothiazide.
Sanjay Bari, Shital Sathe, Pritam Jain, Sanjay Surana   +3 more
doaj   +1 more source

Roselle (Hibiscus sabdariffa L.) extract as an adjunct to valsartan in patients with mild chronic kidney disease: A double-blind randomized controlled clinical trial [PDF]

Avicenna Journal of Phytomedicine
Objective: The objective of this study was to evaluate theeffectiveness of Hibiscus sabdariffa L. extract (HS) as an adjunctto valsartan in the treatment of high blood pressure in patients withmild chronic kidney disease (CKD).Materials and Methods: This
Behdad Dehkhoda, Ayesheh Enayati, Hassan Mirzaei, Somayeh Ghorbani, Mohammad Hadi Soleimani, Saeid Amirkhanlou, Amirhossein Sahebkar   +6 more
doaj   +1 more source

Is the fixed-dose combination of telmisartan and hydrochlorothiazide a good approach to treat hypertension?

Vascular Health and Risk Management, 2007
Marc P Maillard, Michel BurnierService of Nephrology, Department of Internal Medicine, Lausanne University Hospital, SwitzerlandAbstract: Blockade of the renin-angiotensin system with selective AT1 receptor antagonists is recognized as an effective mean ...
Marc P Maillard, Michel Burnier
doaj  

EFFICACY OF FIXED COMBINATION OF VALSARTAN, AMLODIPINE AND HYDROCHLOROTHIAZIDE IN COMPLEX THERAPY OF THE PATIENT OF VERY HIGH CARDIOVASCULAR RISK

Рациональная фармакотерапия в кардиологии, 2015
The high prevalence of arterial hypertension in association with high and very high cardiovascular risk requires widespread use of combined therapy.
I. M. Sokolov, N. A. Zheleznyakova
doaj   +1 more source

New Methodological Approach To Hypertension And Atherosclerosis Treatment [PDF]

Саратовский научно-медицинский журнал, 2009
A new methodological approach has been proposed according to the insufficient results of hypertension (HD) and atherosclerosis (AT) treatment and preventive measures. This method is characterized by the determination and taking into account the phases of
Ya.A. Katz
doaj  

Hydrochlorothiazide combined with exercise training attenuates blood pressure variability and renal dysfunctions in an experimental model of hypertension and ovarian hormone deprivation

FASEB BioAdvances
Considering that blood pressure variability (BPV) has been associated with damage to target organs such as the kidneys, this study aimed to investigate the effects of the association of hydrochlorothiazide (HCTZ) combined with exercise training (CET) on ...
Pietra Petrica Neves, Maycon Junior Ferreira, Tânia Plens Shecaira, Marina Rascio Henriques Dutra, Débora Conte Kimura, Guiomar Nascimento Gomes, Kátia De Angelis   +6 more
doaj   +1 more source