Results 21 to 30 of about 35,149 (271)

Comparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension

JAMA Internal Medicine, 2020
This cohort study compares cardiovascular and safety outcomes of chlorthalidone and hydrochlorothiazide as first-line therapies for adults with hypertension.
G. Hripcsak, M. Suchard, S. Shea, Ruijun Chen, S. You, N. Pratt, D. Madigan, H. Krumholz, P. Ryan, M. Schuemie   +9 more
semanticscholar   +1 more source

Simultaneous Determination of Candesartan and Hydrochlorothiazide in Human Plasma by HPLC-MS/MS

Разработка и регистрация лекарственных средств, 2021
Introduction. Combined drugs have the greatest efficacy and safety in arterial hypertension treatment. The combination of candesartan and hydrochlorothiazide (AT1-receptor antagonist and a thiazide diuretic, respectively) provides high efficiency of ...
P. K. Karnakova, T. N. Komarov, O. A. Archakova, D. S. Shchelgacheva, A. A. Aleshina, N. S. Bagaeva, P. A. Karpova, I. E. Shohin   +7 more
doaj   +1 more source

Use of hydrochlorothiazide in Denmark following publication of skin cancer risk findings

Pharmacoepidemiology and Drug Safety, 2021
The antihypertensive agent hydrochlorothiazide has recently been linked to increased risk of skin cancer. We sought to describe the impact of the dissemination of these findings on the use of hydrochlorothiazide and health care utilization among ...
A. Pottegård, B. Bech, S. Pedersen, B. Christensen   +3 more
semanticscholar   +1 more source

Voltammetric Sensor Based on 1-Benzyl-4-ferrocenyl-1H-[1,2,3]-triazole /Carbon Nanotube Modified Glassy Carbon Electrode; Detection of Hydrochlorothiazide in the Presence of Propranolol

International Journal of Electrochemical Science, 2016
In this work, 1-benzyl-4-ferrocenyl-1H-[1,2,3]-triazole (BFT) and carbon nanotubes has been applied to construct a modified glassy carbon electrode. This modified electrode showed electrocatalytic activity for oxidation of hydrochlorothiazide (HCT) and ...
Sakineh Esfandiari Baghbamidi, Hadi Beitollahi, Somayeh Tajik, Rahman Hosseinzadeh   +3 more
doaj   +1 more source

QbD based development of HPLC method for simultaneous quantification of Telmisartan and Hydrochlorothiazide impurities in tablets dosage form

Practical Laboratory Medicine, 2020
A simple reverse phase liquid chromatographic gradient method has been developed and validated for the simultaneous determination of specified & un-specified impurities of Telmisartan and Hydrochlorothiazide in combination oral solid dosage forms.
A. K. Palakurthi, Thirupathi Dongala, Lakshmi Narasimha Rao Katakam   +2 more
semanticscholar   +1 more source

Association between hydrochlorothiazide exposure and different incident skin, lip and oral cavity cancers: A series of population‐based nested case–control studies

British Journal of Clinical Pharmacology, 2020
Hydrochlorothiazide‐induced photosensitivity may increase squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and lip cancer risk. The aim was to quantify these risks.
D. Morales, A. Pacurariu, J. Slattery, X. Kurz   +3 more
semanticscholar   +1 more source

Design of experiments methodology in studying near-infrared spectral information of model intact tablets : simultaneous determination of metoprolol tartrate and hydrochlorothiazide in solid dosage forms and powder compressibility assessment using near-infrared spectroscopy [PDF]

, 2015
Near-infrared spectroscopy (NIRS) is applied in pharmaceutical industry for monitoring drug content during tablet manufacturing process. NIRS method, once developed and validated, is used over years and it is of critical importance to insure method ...
Vranic, Branko Z.
core   +1 more source

Formulation and Characterisation of a Combination Captopril and Hydrochlorothiazide Microparticulate Dosage Form

Pharmaceutics, 2020
Cardiovascular diseases such as hypertension and cardiac failure in South African children and adolescents are effectively managed long term, using a combination treatment of captopril and hydrochlorothiazide.
Mellisa T. R. Chikukwa, Roderick B. Walker, Sandile M. M. Khamanga   +2 more
doaj   +1 more source

Pharmacoeconomic evaluation of stroke and myocardial infarction prevention in hypertensive patients: Markov model based on the ACCOMPLISH trial

Journal of International Medical Research, 2023
Objective We evaluated the pharmacoeconomics of amlodipine combined with benazepril and hydrochlorothiazide combined with benazepril in the treatment of hypertension using a Markov model to provide an evidence-based reference for clinical drug use ...
Aozi Feng, Weizhao Lin, Li Li, Mengnan Zeng, Jun Lyu   +4 more
doaj   +1 more source

Ambulatory Blood Pressure Reduction With SGLT-2 Inhibitors: Dose-Response Meta-analysis and Comparative Evaluation With Low-Dose Hydrochlorothiazide

Diabetes Care, 2019
OBJECTIVE Sodium–glucose cotransporter (SGLT)-2 inhibitors lower clinic and ambulatory blood pressure (BP), possibly through their natriuretic action. However, it remains unclear whether this BP-lowering effect is dose dependent and different from that ...
P. Georgianos, R. Agarwal
semanticscholar   +1 more source